Search Results for: Allergy

Abstract: Cry1Ac toxin, from Bacillus thuringiensis, is widely used as a biopesticide and expressed in genetically modified (GM) plants used for human and animal consumption. Since Cry1Ac is also immunogenic and able to activate macrophages, it is crucial to thoroughly evaluate the immunological effects elicited after intra-gastric administration. The allergenic potential of purified Cry1Ac was …

Abstract: Several types of pesticides, such as organophosphates, phenoxyacetic acid, and carbamate have a high risk of affecting human health, causing allergic rhinitis and bronchial asthma-like diseases. We used our long-term sensitization method and a local lymph node assay to examine the allergic reactions caused by several types of pesticides. BALB/c mice were topically sensitized …

Abstract: In 1988 a hospital launched a “healthy eating day” in its staff canteen at lunchtime. One dish contained red kidney beans, and 31 portions were served. At 3 pm one of the customers, a surgical registrar, vomited in theatre. Over the next four hours 10 more customers suffered profuse vomiting, some with diarrhoea. All had …

Abstract: Changing existing features of living beings or giving new features to them by changing the natural gene sequence through biotechnological methods is called “genetically modified organisms”, in short “GMO”. Nowadays, lots of food consumed is either totally genetically modified food or a type of food including food components produced by gene modification technology. Improving …

Abstract: For the safety evaluation of genetically engineered crops the potential allergenicity of the newly introduced protein(s) has become an important issue. There is, however, no universal and reliable test system for the evaluation of the allergenic potency of food products. The best known allergy assessment proposal is the careful stepwise process using the IFBC/ILSI …

Abstract: Our objective in the study was to investigate the putative associations of specific pesticides with non-Hodgkin’s Lymphoma [NHL; International Classification of Diseases, version 9 (ICD-9) 200, 202]. We conducted a Canadian multicenter population-based incident, case (n = 517)-control (n = 1506) study among men in a diversity of occupations using an initial postal questionnaire …

Abstract: Since, genetically modified (transgenic) crops have genes which do not belong to their own species, potential risks of these crops on health have brought up in recent years. In general, majority of genes transferred to plants via biotechnological methods are bacteria and virus originated which forms the basis of several problems. Since, transgenic crops …

Abstract: Genetically modified foods (GM foods) are foods derived from genetically modified organisms (GMOs). GMOs have had specific changes introduced into their DNA by genetic engineering techniques. Countries like India that have food security concerns and have small and marginal farmers practicing an integrated type of agriculture have specific problems for which they seek solutions. …

Abstract: Most traits introduced into genetically engineered crops result from the expression of new proteins. As the first step toward assessing the allergenic potential of genetically modified organism (GMO) food, immunologic and physicochemical characterizations are needed. We prepared crude extract from GMO soybeans, wild soybeans, curd, and soy milk and then performed sodium dodecyl sulfate-polyacrylamide …

Abstract: This paper provides an overview of the effects of transgenic plants, also known as Genetically Modified Organisms, and food safety. Modern biotechnologies are powerfull tools in reprogramming life. However, a major problem in the risk assessment of the organisms produced by biotechnology is that the outcome of transformations can not be fully foreseen. Potential …

Abstract: Genetically modified (GM) crops require allergenicity and toxicity assessment of the novel protein(s) to ensure complete safety to the consumers. These assessments are performed in accordance with the guidelines proposed by Codex (2003) and ICMR (2008). The guidelines recommend sequence homology analysis as a preliminary step towards allergenicity prediction, later in vitro experiments may …

Text: “Genetically Modified Foods: Breeding Uncertainty” (Schmidt 2005) overlooked many serious concerns about the environmental and health risks of this new technology. Potential problems from antibiotic-resistant genes used in gene-altered crops, risks from unintended effects of the genetic engineering process, the increases in pesticide use stemming from widespread planting of gene-spliced varieties—these and several other …

Abstract: The safety assessment of genetically modified (GM) plants and their derived food and feed is nowadays a matter of lively debate. Any nutritional consequence of GM food consumption needs to be considered, both in terms of possible changes in the levels of nutrients in the food itself, and in terms of direct or indirect, …

Abstract: This is my expert opinion based on experience and research (full CV attached in Appendix One) in relation to the questions posed by the Commission and outlined in the Summary below. All assertions I make and conclusions that I draw are my opinion. In brief, I am a professor of genetics and molecular biology …

Text: Introduction. With the advent of introducing genetic engineering in agricultural sciences and food production, food safety has become a major issue.[1] The genetic content of the organisms is altered using these techniques that result into genetically engineered organism (plants/animals) also known as genetically modified organisms. Human beings mainly depend upon plants for their food …