GMO Research
Abstract: The quality of diets in rodent feeding trials is crucial. We describe the contamination with environmental pollutants of 13 laboratory rodent diets from 5 continents. Measurements were performed using accredited methodologies. All diets were contaminated with pesticides (1-6 out of 262 measured), heavy metals (2-3 out of 4, mostly lead and cadmium), PCDD/Fs (1-13 …
Text: Влияние диеты, содержащей генетически модифицированную (ГМ) сою, на репродуктивные функции животных изучено недостаточно. Имеющиеся в литературе данные противоречивы. Так, Brake и Evenson [1] не обнаружили негативного воздействия наиболее распространенной ГМ-сои с трансгеном EPSPS CP4 (RR, линия 40.3.2) на сперматогенез у потомства самцов мышей. В то же время другими исследователями были выявлены патологические изменения в семенниках …
Abstract: The experiment with the usage of genetically modified soy in the diet of Wistar rats-females during 6 months was done. The group of animals with the usage of non-modified soy was the comparison group. It was revealed that the morphofunctional state of the adrenal gland significantly activated in both groups. In the part of …
Abstract: Hormonal and histological changes in a tissue of ovaries of rats are studied at long introduction in nutrition GMO. Introduction in nutrition within 6 months of the GMO-soya to practically healthy rats Vistar leads to an acceleration of ageing of ovaries. Keywords: GM soy, Glyphosate tolerant soybean, GTS 40-3-2, Roundup Ready soya, Wistar rats, …
Abstract: We have considered the possible effects of a diet containing genetically modified (GM) soybean on mouse testis. This organ, in fact, is a well known bioindicator and it has already been utilized, for instance, to monitor pollution by heavy metals. In this preliminary study, we have focussed our attention on Sertoli cells, spermatogonia and …
Text: Проводились исследования влияния диеты, содержащей генетически модифицированную (ГМ) сою, устойчивую к гербициду раундапу (Roundup Ready, линия 40.3.2, трансген EPSPS CP4), на морфологическое состояние органов взрослых крыс и выживаемость потомства (группа «ГМ-соя»). В контрольных группах крыс к виварному корму добавляли в таком же количестве традиционную сою Arcon SJ 91-330 (группа «Трад-соя») или ничего не добавляли …
Abstract: This study aimed to evaluate the possibility of DNA sequences from genetically modified plants to persist in the gastrointestinal (GI) tract. PCR analysis and transformation assays were used to study DNA persistence and integrity in various ex vivo and in vivo systems using gnotobiotic rats. DNA studied was either plasmid DNA, naked plant DNA …
Abstract: Kalach 360 SL (KL) is a commercial herbicide which contains 360 g/l of glyphosate used in both agricultural and urban areas throughout the world including Tunisia. We aimed to evaluate the effects of KL on rats’ renal system. Female Wistar rats were divided into three groups: group 1 (n = 6) received a standard diet and served …
Abstract: TT51, with a synthetic Cry1Ab/CryAc gene from Bacillus thuringiensis Berliner, was the first genetically modified (GM) plant officially certificated in China. This study was undertaken to investigate potential embryotoxicity of TT51 on rats. Whole embryo culture (WEC) is an effective method for safety evaluation when culture medium, containing substances derived from GM food, is …
Abstract: Oral administration of 2,4-dichlorophenoxyacetic butyl ester (2,4-Dbe) at a dose of 69 mg/kg/day to nulliparous females had no deleterious effects on either open field (OF) and rotarod performance. By contrast, dams treated with 2,4-Dbe during pregnancy exhibited impairments of OF activity, rotarod performance and improved active avoidance learning (AAL) retention. Administration of 2,4-Dbe to …
Abstract: Research purpose. Identify the presence of unidentified factor transgenic soybean in posterity of rats at her long-term feeding. Object and research methods. Research conducted on white rats which were kept in the vivarium Vinnitsa National Medical University named M.I. Pirogov. Two groups of rats by 10 goals each fed a standard diet vivarium and …
Abstract: Organic soy (OS) and transgenic or genetically modified soy (GMS) were evaluated in the recovery from malnutrition. Ninety-six male Wistar rats weaned on the 21st day were used. 1st phase – malnutrition – 14 days: 24 rats were undernourished with aproteic food free of iron and distributed in 3 groups (n=8); control groups received …
Abstract: In the present study, we evaluated the pesticide and metal concentrations as well as the antimutagenic and mutagenic properties of commercial soybeans (Glycine max). Male Swiss mice were fed diets containing 1%, 10%, or 20% (w/w) transgenic soybeans (BRS Valiosa RR) or parental isogenic conventional soybeans (MG-BR46 Conquista). Cyclophosphamide (50 mg kg−1 b.w.) was …
Abstract: The experiment on Wistar rats with the using of genetically modified and non-modified soy in the diet of pregnant females during gestation and of descendants for 2–3 months life. It was concluded that the foods of genetically modified and unmodified soy are environmental factors that cause stress adaptative reactions that was studied morphologically on …
Abstract: Широкое применение продуктов, содержащих ГМО (ГМ-продуктов), в питании человека и животных обусловливает актуальность исследований, направленных на изучение безопасности их применения. Одним из наиболее объективных методов оценки безопасности употребления ГМ-продуктов является изучение реактивности организма. Индивидуальная реактивность зависит от наследственных, внутриутробных и средовых обстоятельств особи. Адаптационный процесс при действии на организм разных факторов происходит с разной …
To the editor: I was grateful to you for inviting me to discuss some of my experimental results in Nature Biotechnology; however, the Feature entitled “[Genetically modified] GM soybeans and health safety—a controversy reexamined,” as published in the September issue1, presents a flawed picture of my work. Although I thank Bruce Chassy, Val Giddings, Vivian …
Text: Существуют многочисленные данные о негативном воздействии генетически модифицированных организмов (ГМО) на организм млекопитающих. Так, были выявлены патологические изменения в органах при добавлении в корм животных ГМ-картофеля, ГМ-кукурузы, ГМ-гороха и ГМ-сои (Puzstai, 1999; Ewen and Puzstai, 1999; Malatesta et al., 2002, 2003; Prescott et al., 2005; Seralini et al., 2007 и др.). Однако практически нет …
Abstract: These preliminary studies show that GM soybean, a herbicide-resistant roundup, leads to increased mortality and a weakening of part of the newborn rats. Keywords: Roundup Ready soy, GTS 40-3-2, Glyphosate tolerant soybean, Wistar rats, Rodent, GM soybeans, Genetically modified soya, Feeding, Rat, Rodents, Genetically engineered, Transgenic, GMO Citation: Ermakova, I.V. (2006) Genetically modified soy …
To the editor: I am writing concerning the Feature that you ‘authored’ in the September issue. I wish to point out that Irina Ermakova had no opportunity to respond to the criticism of your panel of ‘researchers working in the field’. The lack of an opportunity to face those hostile comments lacks any sense of …
