Journal or Publishing Institution: Journal of Environmental and Analytical Toxicology
Author(s): Krüger, M., Schrödl, W., Neuhaus, J. and Shehata, A.A.
Article Type: Peer Reviewed Study
Record ID: 1309
Abstract: In the present study, thirty dairy cows from each of eight Danish dairy farms were investigated for excretion of glyphosate in urine. Blood serum parameters indicative of cytotoxicity as alkaline phosphatase (AP), glutamate dehydrogenase (GLDH), glutamate oxaloacetate transaminase (GOT), creatinine kinase CK), nephrotoxicity, (urea, creatine), cholesterol and the trace elements as manganese (Mn), cobalt (Co), selenium (Se), copper (Cu) and zinc (Zn) were investigated. All cows excreted glyphosate in their urine but in varying concentrations. Increased levels of GLDH, GOT and CK in cows from all farms demonstrate a possible effect of glyphosate on liver and muscle cells. High urea levels in some farms could be due to nephrotoxicity of glyphosate. Also the unexpected very low levels of Mn and Co were observed in all animals which could be explained due to a strong mineral chelating effect of glyphosate. In contrast the mean levels of Cu, Zn and Se were within the normal reference range. In conclusion, this study gives the first documentation to which extent Danish dairy cattle are exposed to Glyphosate and its impact on blood parameters.
Keywords: Glyphosate; Trace elements; Blood parameters; Dairy cattle; Urine; Liver; Health’ Cow; Cows; Urine
Citation: Krüger, M., Schrödl, W., Neuhaus, J. and Shehata, A.A., 2013. Field investigations of glyphosate in urine of Danish dairy cows. Journal of Environmental and Analytical Toxicology, 3(5), p.100186.