Tshawb nrhiav rau: 2,4-Dichlorophenoxyacetic acid

Cov ntawv nyeem: Hauv lawv tsab xov xwm tsis ntev los no, peb xav tias Wright li al. (1) misrepresented lub peev xwm rau 2,4-dichlorophenoxyacetic acid (2,4-D)-resistant nroj tsuag nyob rau hauv 2,4-D-resistant qoob loo systems thiab exaggerated lub sustainability ntawm lawv mus kom ze los daws cov teeb meem glyphosate-resistant nroj tsuag hauv kev ua liaj ua teb. Wright et al. (1) tshaj tawm txoj kev loj hlob los ntawm Dow AgroSciences ntawm transgenes hauv pob kws, taum pauv, thiab paj rwb ...

Lus Nug: Ib txoj kev tshawb fawb hauv tsev kho mob ntawm tus khub dev tau tshuaj xyuas qhov kev pheej hmoo ntawm kev tsim cov qog nqaij hlav cancer mis uas cuam tshuam nrog kev siv tshuaj hauv tsev thiab hauv tsev. Cov ntaub ntawv los ntawm daim ntawv nug tus tswv tswj hwm tus kheej thiab / lossis kev sib tham hauv xov tooj txog 491 tus neeg mob, 466 kev tswj tsis tu ncua, thiab 479 cov qog qog tau qhia tias cov tswv hauv tsev nrog dev…

Paub meej: Glyphosate, cov khoom xyaw tseem ceeb hauv Roundup®, yog cov tshuaj tua kab mob ntau tshaj plaws hauv ntiaj teb. Nws kuj tseem siv ua ke nrog lwm cov tshuaj tua kab mob zoo, 2,4-D, hauv cov qauv hu ua Enlist Duo®. EPA tau pom zoo siv Enlist Duo® rau qee cov qoob loo suav nrog cov kev hloov kho caj ces kom tiv taus ob qho tshuaj tua kab. Qhov…

Paub meej: Biocides, xws li tshuaj tua kab mob, yog niaj hnub kuaj rau toxicity tab sis tsis rau sublethal cuam tshuam rau microbes. Ntau cov biocides paub tias yuav ua rau muaj kev hloov pauv ntau yam tshuaj tiv thaiv kab mob phenotype. Qhov no tuaj yeem yog vim muaj kev nce ntxiv ntawm cov twj tso kua mis efflux, txo cov synthesis ntawm cov txheej membrane porins, los yog ob qho tib si. Kev nthuav tawm ntawm Escherichia coli…

Paub meej: Kev raug rau 2,4-dichlorophenoxyacetic acid (2,4-D) muaj ntau yam cuam tshuam rau lub paj hlwb xws li kev hloov pauv hauv cov ntsiab lus ntawm neurotransmitters hauv lub hlwb thiab / lossis kev hloov pauv tus cwj pwm, tus nqi myelination, ganglioside qauv [Bortolozzi, A., Duffard, R., Antonelli, M., Evangelista de Duffard, AM, 2002. Nce rhiab heev nyob rau hauv dopamine D(2)-zoo li lub paj hlwb receptors los ntawm 2,4-dichlorophenoxyacetic acid (2,4-D)-exposed thiab …

Paub meej: Kev thauj cov nyom-tsim 2,4-D rau hauv 13 lub tsev tiag tiag tau ntsuas tom qab ob tus tswv tsev thiab kev lag luam siv cov tshuaj tua kab no rau cov nyom nyom. Kev sau cov plua plav hauv pem teb hauv tsib chav ntawm txhua lub tsev, sib haum rau txoj kev nkag, chav nyob, chav noj mov, chav ua noj, thiab tus menyuam chav pw, ob qho tib si ua ntej thiab tom qab thov, qhia tias turf…

Paub meej: Siv Suav hamster V79 hauv vitro cell system tsim los ntsuas kev sib txuas lus ntawm tes, 2,4-dichlorophenoxyacetic acid (2,4-D), 2,4,5-trichlorophenoxyacetic acid (2,4,5-T), thiab ob peb qhov sib xyaw ntawm cov tebchaw no tau sim rau lawv lub peev xwm los cuam tshuam cov txheej txheem lom neeg no. Lub peev xwm ntawm cov tshuaj no los inhibit colony-forming peev xwm ntawm cov hlwb no tau sim ua ntej cov kev tshawb fawb…

Paub meej: Lub Rau Hli, 2015, 26 tus kws tshaj lij los ntawm 13 lub teb chaws tau ntsib ntawm Lub Chaw Haujlwm Saib Xyuas Kev Tshawb Fawb Thoob Ntiaj Teb ntawm Cancer (IARC; Lyon, Fabkis) txhawm rau txheeb xyuas cov kab mob carcinogenicity ntawm cov tshuaj tua kab lindane thiab 1,1,1-trichloro-2,2-bis (4-chlorophenyl) ethane (DDT), thiab tshuaj tua kab mob 2,4-dichlorophenoxyacetic acid (2,4-D). Cov kev ntsuas no yuav raug luam tawm raws li Volume 113 ntawm IARC Monographs. Keywords: 2,4-Dichlorophenoxyacetic Acid, Tsiaj, Carcinogens,…

Paub meej: Cov teebmeem ntawm 2,4-dichlorophenoxyacetic acid (2,4-D) ntawm lub paj hlwb monoamines thiab qib ntshav ntawm cov tshuaj hormones koom nrog hauv cov mis nyuj synthesis thiab ntawm cov mis ejection reflex hauv nas tau soj ntsuam. Dams tau kho nrog 2.5, 5, 15, 25, 50 lossis 70mg 2,4-D / kg bw raws li ob txoj kev sim: (a) los ntawm cov zaub mov tom qab hnub yug ...

Kev paub txog kev noj zaub mov thaum ntxov tau pom tias yog ib qho tseem ceeb hauv kev txiav txim siab qib kev ua haujlwm ntawm cov nas tom qab hauv lub neej, peb tau kawm cov xeeb ntxwv ntawm cov dams uas tau txais 50, 70 lossis 700 mg / kg ntawm 2,4-Dichlorophenoxyacetic acid (2,4 , 16-D) thaum lub caij laus. Cov ntaub so ntswg neonatal thiab lub plab cov ntsiab lus (mis nyuj) tau tshuaj xyuas txog XNUMX tus ncej…

Cov Lus Qhia: Txhawm rau ntsuas lub luag haujlwm ntawm cov tshuaj tua kab mob 2,4-dichlorophenoxyacetic acid (2,4-D) hauv kev txhim kho cov kab mob uas tsis yog Hodgkin's lymphoma (NHL), peb tau ua kev tshawb fawb txog pej xeem, kev tswj xyuas cov ntaub ntawv hauv 66 lub nroog nyob rau sab hnub tuaj. Nebraska. Kev xam phaj hauv xov tooj tau ua nrog 201 tus txiv neej dawb kuaj pom nrog NHL thaum Lub Xya Hli 1, 1983, thiab Lub Rau Hli 30, 1986, thiab nrog 725 tswj. Muaj…

Cov lus piav qhia: Cov tshuaj tua kab mob hormonal tau siv dav, 2,4-dichlorophenoxyacetic acid, thaiv kev loj hlob ntawm meiotic hauv vitro thiab yog li muaj peev xwm cuam tshuam txog ib puag ncig endocrine cuam tshuam nrog kev ua me nyuam ntxov. Txhawm rau kuaj seb qhov kev loj hlob inhibition puas yog nyob ntawm cov protein kinase A, ib qho endogenous maturation inhibitor, oocytes tau microinjected nrog PKI, ib qho PKA inhibitor tshwj xeeb, thiab raug rau 2,4-D. Oocytes ua tsis tiav…

Cov Lus Qhia: Peb tau kawm txog kev ua me nyuam ntawm 32 txiv neej ua liaj ua teb tshuaj tsuag uas raug 2,4-D. Kev tshuaj xyuas phev tau ua tom qab 4 hnub ntawm kev sib deev tsis muaj zog. Cov kev ntsuas ntsuas yog ntim, cov phev suav, mobility thiab morphology. Cov qib raug kwv yees los ntawm kev ntsuas qhov concentration ntawm 2,4-D hauv cov zis. Cov theem tseem ceeb ntawm asthenospermia, necrospermia thiab teratospermia yog…

Paub meej: Mob toxicity thiab genotoxicity ntawm 54.8% 2,4-D-raws li kev lag luam herbicide DMA® tau soj ntsuam ntawm Cnesterodon decemmaculatus (Pisces, Poeciliidae). Thaum cov nyhuv tuag tau raug siv los ua qhov kawg ntawm kev tuag, zaus ntawm micronuclei (MNs), lwm yam kev txawv txav hauv nuclear thiab thawj DNA puas raug soj ntsuam los ntawm tib lub xov tooj ntawm tes gel electrophoresis (SCGE) kev soj ntsuam tau ua haujlwm raws li cov ntsiab lus kawg ...

Paub meej: Cov teebmeem genotoxic ntawm 2,4-D thiab nws cov khoom lag luam derivative 2,4-D DMA tau kawm los ntawm kev ntsuas tus muam chromatid exchange (SCE), cell-cycle progression thiab mitotic index nyob rau hauv tib neeg cov ntshav (WBC) thiab plasma leukocyte kab lis kev cai (PLC). Concentrations ntawm 10, 25, 50 thiab 100 microg herbicide / ml tau siv thaum 72 teev. Hauv WBC, qhov nce tseem ceeb hauv…

Paub meej: 2,4-Dichlorophenoxyacetic acid (2,4-D) yog carcinogenic nyob rau hauv txiv neej thiab poj niam nas thiab tej zaum kuj nyob rau hauv nas. Txiv neej thiab poj niam nas noj 2,4-D tsim muaj qhov tshwm sim ntawm malignant neoplasms. Lymphosarcomas tau nce hauv nas ntawm ob qho tib si poj niam txiv neej, thiab neoplasms ntawm cov qog mammary hauv cov poj niam nas. Txiv neej nas kuj muaj carcinomas ntawm cov kab mob endocrine. 2,4-D…

Paub meej: Cov txiaj ntsig ntawm 105 tus neeg mob nrog cov tshuaj histopathologically lees paub tias tsis yog-Hodgkin's lymphoma (NHL) thiab 335 kev tswj hwm los ntawm cov ntaub ntawv tshaj tawm yav dhau los-tswj kev tshawb fawb ntawm malignant lymphoma tau nthuav tawm ua ke nrog qee qhov kev tshuaj xyuas txuas ntxiv. Tsis muaj kev ua haujlwm yog qhov muaj feem pheej hmoo rau NHL. Kev cuam tshuam rau phenoxyacetic acids yielded, nyob rau hauv lub univariate tsom xam, ib tug odds ratio ntawm 5.5 nrog ib tug 95% ...