Search Results for: Cancer
Non-Hodgkin’s lymphoma and specific pesticide exposures in men: cross-Canada study of pesticides and health
Abstract: Our objective in the study was to investigate the putative associations of specific pesticides with non-Hodgkin’s Lymphoma [NHL; International Classification of Diseases, version 9 (ICD-9) 200, 202]. We conducted a Canadian multicenter population-based incident, case (n = 517)-control (n = 1506) study among men in a diversity of occupations using an initial postal questionnaire …
Biotech crops’ seal of safety does not convince skeptics
Text: Genetically modified organisms (GMOs) have become nearly ubiquitous in U.S.-produced corn, soybeans, and canola, and more than two-thirds of the processed foods Americans consume contain such ingredients. Government agencies and international bodies have repeatedly approved the foods for human consumption while arguing that such bioengineered crops help preserve the environment and could save millions …
The protective role of antioxidants in the defence against ROS/RNS-mediated environmental pollution
Abstract: Overproduction of reactive oxygen and nitrogen species can result from exposure to environmental pollutants, such as ionising and nonionising radiation, ultraviolet radiation, elevated concentrations of ozone, nitrogen oxides, sulphur dioxide, cigarette smoke, asbestos, particulate matter, pesticides, dioxins and furans, polycyclic aromatic hydrocarbons, and many other compounds present in the environment. It appears that increased …
Evaluación de la Salud Colectiva Socio-Ambiental de Monte Maíz
Por expresa solicitud del Municipio de Monte Maíz y de vecinos de la Red de Prevención de Monte Maíz, se realizó una evaluación de la situación sanitaria ambiental del pueblo entre los días 14 y 18 de octubre de 2014. La preocupación de los pobladores radicaba en el aparente aumento del número de personas afectadas …
Conflicts of interests, confidentiality and censorship in health risk assessment: The example of an herbicide and a GMO
Abstract: We have studied the long-term toxicity of a Roundup-tolerant GM maize (NK603) and a whole Roundup pesticide formulation at environmentally relevant levels from 0.1 ppb. Our study was first published in Food and Chemical Toxicology (FCT) on 19 September, 2012. The first wave of criticisms arrived within a week, mostly from plant biologists without experience in toxicology. We …
Malignant lymphoproliferative diseases in occupations with potential exposure to phenoxyacetic acids or dioxins: A register‐based study
Abstract: The Swedish Cancer Environment Register (CER) is a linkage of census data (e.g., on occupations) with the Swedish Cancer Register. It has been used in different studies to generate hypotheses on occupational risk factors for malignant tumors. In this study the risk for malignant lymphoma and multiple myeloma in occupations with potential exposure to …
Unlabeled milk from cows treated with biosynthetic growth hormones: a case of regulatory abdication
Abstract: Levels of insulin-like growth factor-1 (IGF-1) are substantially elevated and more bioactive in the milk of cows hyperstimulated with the biosynthetic bovine growth hormones rBGH, and are further increased by pasteurization. IGF-1 is absorbed from the gastrointestinal tract, as evidenced by marked growth-promoting effects even in short-term tests in mature rats, and absorption is …
Pesticide appliers with mixed pesticide exposure: G-banded analysis and possible relationship to non-Hodgkin’s lymphoma
Abstract: To further investigate the possible relationships between agricultural pesticide exposure and the increased risk of non-Hodgkin’s Lymphoma among farm workers in the north central United States, we performed G-banded chromosome analyses of peripheral blood from workers classified according to primary types of pesticide exposure: herbicides (n = 20), insecticides (n = 18), fumigants (n …
Health risks of genetically modified foods
Abstract: As genetically modified (GM) foods are starting to intrude in our diet concerns have been expressed regarding GM food safety. These concerns as well as the limitations of the procedures followed in the evaluation of their safety are presented. Animal toxicity studies with certain GM foods have shown that they may toxically affect several …
Transgenerational effects of maternal exposure to chemicals on the functional development of the brain in the offspring
Abstract: In order to prevent health risk from environmental chemicals, particularly for progeny, we have been performing a risk assessment for various chemicals including therapeutic agents. This paper reports the functional effects of maternal exposure to psychoactive drugs, anticancer drugs, or herbicides on the offspring of rats. Maternal exposure to imipramine in a dose equivalent …
Concerns over use of glyphosate-based herbicides and risks associated with exposures: a consensus statement
Abstract: The broad-spectrum herbicide glyphosate (common trade name “Roundup”) was first sold to farmers in 1974. Since the late 1970s, the volume of glyphosate-based herbicides (GBHs) applied has increased approximately 100-fold. Further increases in the volume applied are likely due to more and higher rates of application in response to the widespread emergence of glyphosate-resistant …
A comparative study of phytochemical composition of genetically and non-genetically modified soybean (Glycine max L.) and evaluation of antitumor activity
Abstract: Colon cancer is one of the major causes of cancer mortality worldwide. The analysed feeds, containing non-genetically modified (GM) soybean and Roundup Ready soybean, showed a different polyphenolic content and lipophilic composition. Non-GM soybean extract possessed twice the polyphenolic content of GM soybean and the highest number of sterols. Among them, γ-sitosterol was found …
Embryonic cell cycle for risk assessment of pesticides at the molecular level
Abstract: Cell cycle mechanisms are highly conserved from unicellular eukaryotes to complex metazoans including humans. Abnormalities in the regulation of the cell cycle result in death or diseases such as cancer. Early development of sea urchin has proved to be a powerful model for cell division studies and offers the opportunity to study synchronous cell …
GMOs, herbicides, and public health
Text: Genetically modified organisms (GMOs) are not high on most physicians’ worry lists. If we think at all about biotechnology, most of us probably focus on direct threats to human health, such as prospects for converting pathogens to biologic weapons or the implications of new technologies for editing the human germline. But while those debates …
Detection of herbicides in the urine of pet dogs following home lawn chemical application
Abstract: Exposure to herbicide-treated lawns has been associated with significantly higher bladder cancer risk in dogs. This work was performed to further characterize lawn chemical exposures in dogs, and to determine environmental factors associated with chemical residence time on grass. In addition to concern for canine health, a strong justification for the work was that …
Genetically modified crops and human health
Abstract: Since, genetically modified (transgenic) crops have genes which do not belong to their own species, potential risks of these crops on health have brought up in recent years. In general, majority of genes transferred to plants via biotechnological methods are bacteria and virus originated which forms the basis of several problems. Since, transgenic crops …
Carcinogenicity of tetrachlorvinphos, parathion, malathion, diazinon, and glyphosate
Abstract: In March, 2015, 17 experts from 11 countries met at the International Agency for Research on Cancer (IARC; Lyon, France) to assess the carcinogenicity of the organophosphate pesticides tetrachlorvinphos, parathion, malathion, diazinon, and glyphosate. Keywords: cancer, carcinogenicity, organophosphate, pesticides, tetrachlorvinphos, parathion, malathion, diazinon, glyphosate, rodent, animal, human Citation: Guyton, K.Z., Loomis, D., Grosse, Y., …
Awareness of health impacts of genetically modified foods in India
Abstract: Genetically modified foods (GM foods) are foods derived from genetically modified organisms (GMOs). GMOs have had specific changes introduced into their DNA by genetic engineering techniques. Countries like India that have food security concerns and have small and marginal farmers practicing an integrated type of agriculture have specific problems for which they seek solutions. …
Risks associated with glyphosate weedkiller resurface
Text: As journalists, we have dug into the controversy over the suspected carcinogenicity of the herbicide glyphosate (see B. Url Nature 553, 381; 2018). We searched hundreds of internal documents from its manufacturer, Monsanto, released for pending lawsuits (see go.nature.com/2tfpbwy). We feel that our and others’ findings (N. Ghisi et al. Chemosphere 145, 42–54; 2016) …
Herbicide Factsheet 2,4-D
Abstract: 2,4-D is one of the most widely used herbicides in the world. It is commonly used on rangeland and pasture, in the production of wheat, and on home lawns. Symptoms of 2,4-D poisoning in exposed people include irritation and inflammation of eyes and skin, hives, nausea, vomiting, throat irritation, headache, dizziness, coughing, and difficulty …