Search Results for: Histologic

Abstract: A histological finding of liver and kidney tissues of yellow mystus, Hemibagrus filamentus (Fang and Chaux, 1949), collected from the Tapee River (Chawang District, Nakhon Si Thammarat Province, Thailand) was conducted to examine the pathological lesions. Lesions, including cellular swelling, hydropic degeneration, or vacuolation of hepatocytes were found. From this, coagulative necrosis with pyknotic …

Abstract: This study was carried out to investigate the toxicity of Roundup, aglyphosate-containing herbicide to the earthworm Nsukkadrilus mbae and the associated histological changes. One hundred and sixty fiveearthworms were randomly divided into five groups and exposed to different concentrations of glyphosate (0.0, 13.0, 52.0, 117.0 and 207 mg/Kg soil) for 96 h. The mortality …

Abstract: Summary the article discusses the results of electronic microscopic researches of the rats’ liver of the third generation which were fed with the genetically modified and traditional soybean. Object of the research were 42 rats of the Wistar line, weight of 160–180 g, age of 3.5–4 months. Three groups were formed, 14 rats in each …

Abstract: Sexual differentiation in the brain takes place from late gestation to the early postnatal days. This is dependent on the conversion of circulating testosterone into estradiol by the enzyme aromatase. The glyphosate was shown to alter aromatase activity and decrease serum testosterone concentrations. Thus, the aim of this study was to investigate the effect …

Abstract: This study shows that a diet including insect-resistant Bt176 maize, fed to 53 ewes and their progeny for 3 years, did not have adverse effects on their health or performance and that no horizontal gene transfer to ruminal microorganisms or animal tissues was detected. No differences were observed regarding performance, reproductive traits, haematological parameters, …

Abstract: Effects of exposure to contaminants such as pesticides along with exposure to pathogens have been listed as two major contributors to the global crisis of declining amphibian populations. These two factors have also been linked in explanations of the causes of these population declines. We conducted a combined exposure experiment to test the hypothesis …

Abstract: Atrazine (AZ) and glyphosate (GL) are herbicides that are widely applied to cereal crops in Egypt. The present study was designed to investigate the response of the snail Biomphalaria alexandrina (Mollusca: Gastropoda) as a bioindicator for endocrine disrupters in terms of steroid levels (testosterone (T) and 17β-estradiol (E)), alteration of microsomal CYP4501B1-like immunoreactivity, total …

Abstract: The herbicide Quizalofop-P-ethyl (QpE) exerts toxic effects in fish, but limited information is currently available on its effects on the endocrine system. In the current study, adult zebrafish (Danio rerio) were exposed to different concentrations (0, 2, 20, 200 μg/L) of QpE for 30 days. In males, QpE exposure significantly increased plasma estradiol (E2) …

Abstract: Genetically modified (GM) crops have been commercially available for human and animal consumption since the 1990s. The safety evaluations are based on the concept of substantial equivalence, which assumes that the toxicity of a product can be investigated by assessing the toxicity of individual components of the product and not the product as a …

Abstract: Glyphosate [N-(phosphonomethyl)-glycine] is a broad-spectrum, non-selective, post-emergence herbicide that is extensively used in agriculture. Published data referring to the effects of this product on human health are contradictory. We showed previously that long-term treatment of rats with low doses of Glyphosate-Biocarb® may induce hepatic histological changes and bleeding without decreasing platelet counts. The aim of …

Abstract: Background Glyphosate-based herbicides (GBH) are the major pesticides used worldwide. Converging evidence suggests that GBH, such as Roundup, pose a particular health risk to liver and kidneys although low environmentally relevant doses have not been examined. To address this issue, a 2-year study in rats administering 0.1 ppb Roundup (50 ng/L glyphosate equivalent) via …

Abstract: Background Glyphosate-based herbicides (GBH) are the major pesticides used worldwide. Converging evidence suggests that GBH, such as Roundup, pose a particular health risk to liver and kidneys although low environmentally relevant doses have not been examined. To address this issue, a 2-year study in rats administering 0.1 ppb Roundup (50 ng/L glyphosate equivalent) via …

Abstract: 2,4-Dichlorophenoxyacetic acid (2,4-D) is a selective weedkiller which works by uncoupling oxidative phosphorylation and is in widespread use. It is known as “agent orange”. A 65 year old man had acute hepatitis, thought to be caused by exposure to 2,4-D. The patient ingested 2,4-D as a result of habitual licking of his golf ball. Clinical …

Abstract: The present study was designed to evaluate the impact of feeding a line of genetically modified cotton seeds (Bt cotton seeds) to that of standard diet and reference diet (Non-Bt cotton seeds) on growth, metabolism in albino rats. Non-Bt and Bt cotton seeds were incorporated into the diet of the albino rats at a …

Abstract: Glufosinate-ammonium, a component of the herbicide Basta, is one of the most extensively used pesticides worldwide. In this study, we assessed subchronic and chronic toxicities of Basta and its histopathological effects on the marine medaka Oryzias dan- cena. Marine medaka were exposed to 0, 2, 4, or 8 mg/L of Basta for 28 or …

Abstract: We evaluated the toxicity of hepatic, hematological, and oxidative effects of glyphosate-Roundup® on male and female albino Swiss mice. The animals were treated orally with either 50 or 500 mg/kg body weight of the herbicide, on a daily basis for a period of 15 days. Distilled water was used as control treatment. Samples of …

Abstract: Mineral nutrients are routinely applied to boost crop yields and improve overall plant health and quality. Their judicious use in production agriculture, horticulture, and environmental settings is critical for improved production efficiency and a sustainable ecosystem. The nutrition of a plant determines in large measure its resistance or susceptibility to disease, its histological or …

Abstract: The effects of glufosinate ammonium on embryonic development in mice were examined using whole embryo and micromass cultures of midbrain and limb bud cells. In day 8 embryos cultured for 48 hr, glufosinate caused significant overall embryonic growth retardation and increased embryolethality to 37.5% at 10 micrograms/ml (5.0 x 10(-5) M). All embryos in …

Abstract: Glufosinate ammonium, which is a component of the herbicide BASTA, is a phosphinic analog of glutamic acid. Its activity is related to the inhibition of glutamine synthetase. Previous studies demonstrated that glufosinate has no teratogenic potential in rats and rabbits in vivo. In the present study, we determined whether glufosinate could affect embryonic development …

To the editor: Your May 29 editorial1 about the health risks of genetically modified (GM) food was apposite and addresses some of the important medical issues vigorously. It beggars belief that “badly designed, poorly carried out, inaccurately interpreted experiments” could have perpetuated such profound public debate for almost a year. Regrettably, among the correspondents who …