Search Results for: Cancer
Occurrence of glyphosate and AMPA residues in soy-based infant formula sold in Brazil
Abstract: Glyphosate is an herbicide widely used in the world, being applied in several crops, among them soybeans. Recently, glyphosate and its metabolite aminomethylphosphonic acid (AMPA) have been identified as possible contributors to the emergence of various diseases such as autism, Parkinson’s and Alzheimer’s diseases, as well as cancer. The child population-consuming cereal-based foods is …
Glyphosate–a non-toxic pesticide?
Abstract: Glyphosate is currently the most commonly applied herbicide and its use is still growing. Nowadays, over 50 commercial preparations containing this compound are used, and these formulations are much more toxic than their active compound, glyphosate, owing to the presence of many surfactants and carrier compounds. Toxicological investigations provide evidence that glyphosate is an …
Genetically modified foods and the probable risks on human health
Abstract: Changing existing features of living beings or giving new features to them by changing the natural gene sequence through biotechnological methods is called “genetically modified organisms”, in short “GMO”. Nowadays, lots of food consumed is either totally genetically modified food or a type of food including food components produced by gene modification technology. Improving …
Agricultural exposures and non-Hodgkin’s lymphoma
Abstract: Farmers have an increased risk of non-Hodgkin’s lymphoma (NHL), several studies have found increased risks of NHL among producers or sprayers of pesticides. The findings are markedly inconsistent across countries and studies, but overall there is evidence of an increased risk among production workers and professional pesticide sprayers with heavy exposures. However, this increased …
Genetic engineering of animals: Ethical issues, including welfare concerns
Text: The genetic engineering of animals has increased significantly in recent years, and the use of this technology brings with it ethical issues, some of which relate to animal welfare — defined by the World Organisation for Animal Health as “the state of the animal…how an animal is coping with the conditions in which it …
Exogenous plant MIR168a specifically targets mammalian LDLRAP1: evidence of cross-kingdom regulation by microRNA
Abstract: Our previous studies have demonstrated that stable microRNAs (miRNAs) in mammalian serum and plasma are actively secreted from tissues and cells and can serve as a novel class of biomarkers for diseases, and act as signaling molecules in intercellular communication. Here, we report the surprising finding that exogenous plant miRNAs are present in the …
Fast food fever: reviewing the impacts of the Western diet on immunity
Abstract: While numerous changes in human lifestyle constitute modern life, our diet has been gaining attention as a potential contributor to the increase in immune-mediated diseases. The Western diet is characterized by an over consumption and reduced variety of refined sugars, salt, and saturated fat. Herein our objective is to detail the mechanisms for the …
A case-control study of non-Hodgkin’s lymphoma and the herbicide 2,4-dichlorophenoxyacetic acid (2, 4-D) in eastern Nebraska
Abstract: To evaluate the role of the herbicide 2,4-dichlorophenoxyacetic acid (2,4-D) in the development of non-Hodgkin’s lymphoma (NHL), we conducted a population-based, case-control study in 66 counties in eastern Nebraska. Telephone interviews were conducted with 201 white men diagnosed with NHL between July 1, 1983, and June 30, 1986, and with 725 controls. There was …
Ignoring adjuvant toxicity falsifies the safety profile of commercial pesticides
Abstract: Commercial formulations of pesticides are invariably not single ingredients. Instead they are cocktails of chemicals, composed of a designated pesticidal “active principle” and “other ingredients,” with the latter collectively also known as “adjuvants.” These include surfactants, antifoaming agents, dyes, etc. Some adjuvants are added to influence the absorption and stability of the active principle …
Carcinogenicity of lindane, DDT, and 2,4-dichlorophenoxyacetic acid
Abstract: In June, 2015, 26 experts from 13 countries met at the International Agency for Research on Cancer (IARC; Lyon, France) to assess the carcinogenicity of the insecticides lindane and 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane (DDT), and the herbicide 2,4-dichlorophenoxyacetic acid (2,4-D). These assessments will be published as Volume 113 of the IARC Monographs. Keywords: 2,4-Dichlorophenoxyacetic Acid, Animals, Carcinogens, …
Evaluation on edible safety of genetically modified soy oil by novel system
Abstract: Objective: In the present study, the functions and edible safety of imported genetically modified (GM) and natural soy oils were comparatively evaluated by the novel BDI-GS (Benefit-Damage Index & General Scores) evaluation system. Methods: The healthy ICR (Institute of Cancer Research) mice during linear growth were selected as subject. The judgment of edible safety …
Cytotoxic and DNA-damaging properties of glyphosate and Roundup in human-derived buccal epithelial cells
Abstract: Glyphosate (G) is the largest selling herbicide worldwide; the most common formulations (Roundup, R) contain polyoxyethyleneamine as main surfactant. Recent findings indicate that G exposure may cause DNA damage and cancer in humans. Aim of this investigation was to study the cytotoxic and genotoxic properties of G and R (UltraMax) in a buccal epithelial …
The high cost of pesticides: human and animal diseases
Abstract: A significant degradation in the health of wild animals in Montana has been recorded over the past two decades. We surmise that the health issues are related to pesticide exposure. We present some of the evidence of the deterioration of the health in wildlife, which we used to inspire investigations on human health in …
Glyphosate-induced stiffening of HaCaT keratinocytes, a Peak Force Tapping study on living cells
Abstract: The skin is the first physiological barrier, with a complex constitution, that provides defensive functions against multiple physical and chemical aggressions. Glyphosate is an extensively used herbicide that has been shown to increase the risk of cancer. Moreover there is increasing evidence suggesting that the mechanical phenotype plays an important role in malignant transformation. …
Exposure to pesticides as risk factor for non-Hodgkin’s lymphoma and hairy cell leukemia: Pooled analysis of two Swedish case-control studies
Abstract: Increased risk for non-Hodgkin’s lymphoma (NHL) following exposure to certain pesticides has previously been reported. To further elucidate the importance of phenoxyacetic acids and other pesticides in the etiology of NHL a pooled analysis was performed on two case-control studies, one on NHL and another on hairy cell leukemia (HCL), a rare subtype of …
Innate immune changes in the peripheral blood of Chronic Fatigue Syndrome patients: Risk factors for disease progression and management
Abstract: Chronic Fatigue Syndrome (CFS) is recognized by the WHO as an alternative name for Myalgic Encephalomyelitis, which has been classified as a disease of the central nervous system since 1969. The concept that chronic microbial infection drives constant activation of the innate immune system through alterations in the production of innate immune cells and …
Immunological changes among farmers exposed to phenoxy herbicides: Preliminary observations
Abstract: OBJECTIVES. To evaluate short term immunological changes after agricultural exposure to commercial formulations of chlorophenoxy herbicides. METHODS. Blood samples were collected from 10 farmers within seven days before exposure, one to 12 days after exposure, and again 50 to 70 days after exposure. Whole blood was used to count lymphocyte subsets with monoclonal antibodies. …
About the dangers of genetically modified organisms in food: The situation in Russia and the world
Abstract: GMOs as weapons of mass destruction – a report by IV Ermakova on the impact of genetically modified products on the human body and the ecosystem. Keywords: dangers, genetically modified organisms, food, Russia, infertility, cancer, allergic reactions, mortality, people, animals, biodiversity, environmental degradation Citation: Ermakova, I.V. (2005) About the dangers of genetically modified organisms …
Pathobiological effects of genetically modified organisms (transgenes) on animal and human health
Abstract: Genetically modified organisms (transgenes) are increasingly being used in biology and medicine for genetic research (genetic engineering), vaccines, hormones, enzymes, and for modeling a variety of ailments, as well as commercial purposes. However, the use of genetically modified food is accompanied by significant risks to human and animal health. This paper presents a general …
A new concept in (adenoviral) oncogenesis: Integration of foreign DNA and its consequences
Abstract: A new concept for viral oncogenesis is presented which is based on experimental work on the chromosomal integration of adenovirus DNA into mammalian genomes. The mechanism of adenovirus DNA integration is akin to non-sequence-specific insertional recombination in which patch homologies between the recombination partners are frequently observed. This reaction has been imitated in a …
Genetically Modified Foods – A Review
Abstract: Genetic engineering has a wide scope in future world. Several profits are made from genetic engineering. One of which is genetically modified foods. It is created by modifying the genes in the organisms by inserting desirable traits in organism. It helps to meet the demands of food requirement and increase the resistance of plants …
Integrative assessment of multiple pesticides as risk factors for non-Hodgkin’s lymphoma among men
Abstract: Methods. During the 1980s, the National Cancer Institute conducted three case-control studies of NHL in the midwestern United States. These pooled data were used to examine pesticide exposures in farming as risk factors for NHL in men. The large sample size (n = 3417) allowed analysis of 47 pesticides simultaneously, controlling for potential confounding …