Search Results for: Cancer

Abstract: Glyphosate is the active ingredient in the pervasive herbicide, Roundup, and its usage, particularly in the United States, has increased dramatically in the last two decades, in step with the widespread adoption of Roundup®-Ready core crops. The World Health Organization recently labelled glyphosate as “probably carcinogenic.” In this paper, we review the research literature, …

Abstract: Glyphosate is an active ingredient of the most widely used herbicide and it is believed to be less toxic than other pesticides. However, several recent studies showed its potential adverse health effects to humans as it may be an endocrine disruptor. This study focuses on the effects of pure glyphosate on estrogen receptors (ERs) …

Abstract: The causal link between GM food and human health is proposed to be the scrambling of genes in DNA by low-level UV radiation. GM stands for genetically modified. Modern agriculture controls weeds by spraying Roundup containing water and Glyphosate onto crop fields. To enhance Glyphosate penetration through weed leaves, the adjuvant POEA is added …

Abstract: The International Agency for Research on Cancer (IARC) Monographs Programme identifies chemicals, drugs, mixtures, occupational exposures, lifestyles and personal habits, and physical and biological agents that cause cancer in humans and has evaluated about 1000 agents since 1971. Monographs are written by ad hoc Working Groups (WGs) of international scientific experts over a period …

Abstract: Objective: Agricultural risk factors for lymphohematopoeitic cancers (LHC) in Hispanic farm workers in California were examined in a nested case–control study embedded in a cohort of 139,000 ever members of a farm worker labor union in California. Methods: Crop and pesticide exposures were estimated by linking county/month and crop specific job history information from …

Abstract: We reviewed epidemiologic evidence related to occupational pesticide exposures and cancer incidence in the Agricultural Health Study (AHS) cohort. Studies were identified from the AHS publication list available at http://aghealth.nci.nih.gov as well as through a Medline/PubMed database search in March 2009. We also examined citation lists. Findings related to lifetime-days and/or intensity-weighted lifetime-days of …

To the editor: In a previous work published 4 years ago, an arrest of tumor cell proliferation was obtained with dichloroacetate, an inhibitor of pyruvate dehydrogenase kinase, aiming to dephosphorylate and activate pyruvate dehydrogenase (PDH) [1]. This observation indicates that it may be useful to act as well, on other tumor cell enzymes that change …

Abstract: We recently proposed that deficient cellular interactions in endocrine pancreas were a primary cause for cancer. Normally, insulin secreting beta cells release in parallel GABA, for inhibiting neighboring alpha and delta cells, releasing glucagon and somatostatin respectively. A deficiency of GABA release, will lead to a hybrid anaboliccatabolic metabolism, mediated by insulin and glucagon. …

Abstract: Background – Recently it was reported that a Swedish professor in environmental health has for decades worked as a consultant for Philip Morris without reporting his employment to his academic employer or declaring conflicts of interest in his research. The potential for distorting the epidemiological assessments of hazard and risk through paid consultants, pretending …

Abstract: Background. Argentina, Brazil, Paraguay and Uruguay farm transgenic seeds glyphosate resistant. Argentina annually utilizes 240,000 tonnes of glyphosate in agriculture. A change in the profile of morbidity and mortality is perceived in agricultural areas; cancer seems to prevail. Monte Maíz is a typical argentine agricultural town with 8000 inhabitants; the Mayor and residents of …

Text: Yu and Rohan (1) are to be commended for their comprehensive literature review of the mitogenic and apoptotic actions of insulin-like growth factor (IGF)-I and of the epidemiologic evidence incriminating elevated levels of circulating IGF with excess risks of breast, colorectal, prostate, and other cancers. This evidence is supported by the excess risks of …

Abstract: Glyphosate is a broad-spectrum herbicide that is one of the most frequently applied pesticides in the world. Although there has been little consistent evidence of genotoxicity or carcinogenicity from in vitro and animal studies, a few epidemiologic reports have indicated potential health effects of glyphosate. We evaluated associations between glyphosate exposure and cancer incidence …