Search Results for: Inflammation
Glyphosate-rich air samples induce IL-33, TSLP and generate IL-13 dependent airway inflammation
Abstract: Several low weight molecules have often been implicated in the induction of occupational asthma. Glyphosate, a small molecule herbicide, is widely used in the world. There is a controversy regarding a role of glyphosate in developing asthma and rhinitis among farmers, the mechanism of which is unexplored. The aim of this study was to …
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Search the primary studies database using one of the pre-defined keyword searches below. # 2,4-Dichlorophenoxyacetic acid (2,4-D) 35S A Acetylcholinesterase Aegilops cylindrica Aflatoxin Africa African Catfish (Clarias Gariepinus) African clawed frog (Xenopus laevis) Agrobacterium Agroecology Agrostis Agrostis stolonifera Alfalfa (Medicago sativa) Allergy Alpaida Veniliae Amaranthus palmeri Amaranthus tuberculatus Ambrosia artemisiifolia Ambystoma gracile Ambystoma laterale Ambystoma …
Study of the allergenic potential of Bacillus thuringiensis Cry1Ac toxin following intra-gastric administration in a murine model of food-allergy
Abstract: Cry1Ac toxin, from Bacillus thuringiensis, is widely used as a biopesticide and expressed in genetically modified (GM) plants used for human and animal consumption. Since Cry1Ac is also immunogenic and able to activate macrophages, it is crucial to thoroughly evaluate the immunological effects elicited after intra-gastric administration. The allergenic potential of purified Cry1Ac was …
A novel hypothesis for atherosclerosis as a cholesterol sulfate deficiency syndrome
Abstract: Background – Despite a vast literature, atherosclerosis and the associated ischemia/reperfusion injuries remain today in many ways a mystery. Why do atheromatous plaques make and store a supply of cholesterol and sulfate within the major arteries supplying the heart? Why are treatment programs aimed to suppress certain myocardial infarction risk factors, such as elevated …
Complete genes may pass from food to human blood
Abstract: Our bloodstream is considered to be an environment well separated from the outside world and the digestive tract. According to the standard paradigm large macromolecules consumed with food cannot pass directly to the circulatory system. During digestion proteins and DNA are thought to be degraded into small constituents, amino acids and nucleic acids, respectively, …
Glyphosate’s suppression of cytochrome P450 enzymes and amino acid biosynthesis by the gut microbiome: pathways to modern diseases
Abstract: Glyphosate, the active ingredient in Roundup®, is the most popular herbicide used worldwide. The industry asserts it is minimally toxic to humans, but here we argue otherwise. Residues are found in the main foods of the Western diet, comprised primarily of sugar, corn, soy and wheat. Glyphosate’s inhibition of cytochrome P450 (CYP) enzymes is …
Transgenic expression of bean alpha-amylase inhibitor in peas results in altered structure and immunogenicity
Abstract: The development of modern gene technologies allows for the expression of recombinant proteins in non-native hosts. Diversity in translational and post-translational modification pathways between species could potentially lead to discrete changes in the molecular architecture of the expressed protein and subsequent cellular function and antigenicity. Here, we show that transgenic expression of a plant …
Influence of genetically modified soybean morphology of some of the digestive system in the offspring of rats
Abstract: Цель исследования. Изучение изменений двенадцатиперстной кишки, поджелудочной железы и печени потомства крыс, получавших генетически модифицированную (ГМ) сою. Материалы и методы. Объект исследования – третье поколение крыс (n=10) получавших (ГМ) сою. Контрольная группа – 10 крыс, получавших стандартный виварный рацион. Морфологический материал подвергался стандартной проводке и заливке в парафин, препараты окрашивали гематоксилин – эозином. На …
Influence of long term use of genetically modified soybeans on some morphofunctional indicators in pancreas of rats in the experiment
Abstract: настоящее время генетически модифицированные продукты, в том числе и соевые бобы, получили широкое распространение на российском рынке. Генетически модифицированную (ГМ) сою обнаруживают в молочных, мясных, хлебобулочных продуктах, детском питании и даже косметике. До настоящего времени вопрос о безопасности длительного употребления генетически модифицированных организмов для млекопитающих и их потомства остается спорным. По данным ряда авторов …
Fast food fever: reviewing the impacts of the Western diet on immunity
Abstract: While numerous changes in human lifestyle constitute modern life, our diet has been gaining attention as a potential contributor to the increase in immune-mediated diseases. The Western diet is characterized by an over consumption and reduced variety of refined sugars, salt, and saturated fat. Herein our objective is to detail the mechanisms for the …
A hypothesis regarding the molecular mechanism underlying dietary soy-induced effects on seizure propensity
Abstract: Numerous neurological disorders including fragile X syndrome, Down syndrome, autism, and Alzheimer’s disease are co-morbid with epilepsy. We have observed elevated seizure propensity in mouse models of these disorders dependent on diet. Specifically, soy-based diets exacerbate audiogenic-induced seizures in juvenile mice. We have also found potential associations between the consumption of soy-based infant formula …
Genetically Modified Foods – A Review
Abstract: Genetic engineering has a wide scope in future world. Several profits are made from genetic engineering. One of which is genetically modified foods. It is created by modifying the genes in the organisms by inserting desirable traits in organism. It helps to meet the demands of food requirement and increase the resistance of plants …
Herbicide Factsheet 2,4-D
Abstract: 2,4-D is one of the most widely used herbicides in the world. It is commonly used on rangeland and pasture, in the production of wheat, and on home lawns. Symptoms of 2,4-D poisoning in exposed people include irritation and inflammation of eyes and skin, hives, nausea, vomiting, throat irritation, headache, dizziness, coughing, and difficulty …
