Search Results for: Pregnant
Effect of the herbicide glyphosate on enzymatic activity in pregnant rats and their fetuses
Abstract: To prevent health risk from environmental chemicals, particularly for progeny, we have studied the effects of the herbicide glyphosate on several enzymes of pregnant rats. Glyphosate is an organophosphorated nonselective agrochemical widely used in many countries including Argentina and acts after the sprout in a systemic way. We have studied three cytosolic enzymes: isocitrate …
Search by Keyword
Search the primary studies database using one of the pre-defined keyword searches below. # 2,4-Dichlorophenoxyacetic acid (2,4-D) 35S A Acetylcholinesterase Aegilops cylindrica Aflatoxin Africa African Catfish (Clarias Gariepinus) African clawed frog (Xenopus laevis) Agrobacterium Agroecology Agrostis Agrostis stolonifera Alfalfa (Medicago sativa) Allergy Alpaida Veniliae Amaranthus palmeri Amaranthus tuberculatus Ambrosia artemisiifolia Ambystoma gracile Ambystoma laterale Ambystoma …
Perinatal exposure to a glyphosate-based herbicide impairs female reproductive outcomes and induces second-generation adverse effects in Wistar rats
Abstract: Glyphosate-based herbicides (GBHs) are the most globally used herbicides raising the risk of environmental exposition. Here, we investigated whether perinatal exposure to low doses of a GBH alters the female reproductive performance, and/or induced second-generation effects related to congenital anomalies or growth alterations. Pregnant rats (F0) received a GBH through food, in a dose …
On the fate of orally ingested foreign DNA in mice: chromosomal association and placental transmission to the fetus
Abstract: We have previously shown that, when administered orally to mice, bacteriophage M13 DNA, as a paradigm foreign DNA without homology to the mouse genome, can persist in fragmented form in the gastrointestinal tract, penetrate the intestinal wall, and reach the nuclei of leukocytes, spleen and liver cells. Similar results were obtained when a plasmid …
Effect of 2,4-dichlorophenoxyacetic acid on rat maternal behavior
Abstract: Exposure to 2,4-dichlorophenoxyacetic acid (2,4-D) has several deleterious effects on the nervous system such as alterations in the concentrations of neurotransmitters in the brain and/or behavioral changes, myelination rate, ganglioside pattern [Bortolozzi, A., Duffard, R., Antonelli, M., Evangelista de Duffard, A.M., 2002. Increased sensitivity in dopamine D(2)-like brain receptors from 2,4-dichlorophenoxyacetic acid (2,4-D)-exposed and …
Result of research of mutagenic activity of a genetically modified product in experiments on laboratory animals
Abstract: The aim of the research was assessment of mutagenic activity of the genetically modified product (a commercial product from soybean) in an experiment on laboratory animals. In the course of work in experienced groups the parameter of “unsuccessful” incubation of embryos in females of white not purebred rats is revealed. In control group the …
Increased secretion of insulin-like growth factor I into milk of cows treated with recombinantly derived bovine growth hormone
Abstract: Six lactating, non-pregnant Jersey cows were given subcutaneous injections of recombinantly derived bovine growth hormone for 7 d. Milk yield was increased by 4.5 kg/d on d 7, compared with the average yield of 10.7 +/- 0.4 kg/d (mean +/- s.e.m.) for the 7 d preceding treatment. Concentrations of insulin-like growth factor I (IGF-I) …
A survey of genetically modified foods consumed, health implications and recommendations for public health food safety in Trinidad
Abstract: Genetically modified foods provide one of the major challenges facing the food industry in the twenty-first century worldwide. The safety of genetically modified foods are being questioned by scientists, researchers and doctors as it is believed that these foods may pose a serious public health risk, especially for the young, aged, pregnant and immunocompromised …
Glyphosate and Paraquat in Maternal and Fetal Serums in Thai Women
Abstract: OBJECTIVES: This longitudinal study measured the glyphosate and paraquat concentrations found in maternal and umbilical cord serum in 82 pregnant women who gave birth in three provinces of Thailand. METHODS: Through questionnaires and biological samples collected at childbirth, factors such as personal characteristics, family members occupation, agricultural activities, and herbicide use in agricultural work …
Morphofunctional adrenal state in adult descendants with the diet by genetically modified soy
Abstract: The experiment on Wistar rats with the using of genetically modified and non-modified soy in the diet of pregnant females during gestation and of descendants for 2–3 months life. It was concluded that the foods of genetically modified and unmodified soy are environmental factors that cause stress adaptative reactions that was studied morphologically on …
Why genetically modified food needs reconsideration before consumption
Text: Introduction. With the advent of introducing genetic engineering in agricultural sciences and food production, food safety has become a major issue.[1] The genetic content of the organisms is altered using these techniques that result into genetically engineered organism (plants/animals) also known as genetically modified organisms. Human beings mainly depend upon plants for their food …
Exposure to a glyphosate-based herbicide during pregnancy and lactation induces neurobehavioral alterations in rat offspring
Abstract: The impact of sub-lethal doses of herbicides on human health and the environment is a matter of controversy. Due to the fact that evidence particularly of the effects of glyphosate on the central nervous system of rat offspring by in utero exposure is scarce, the purpose of the present study was to assess the …
Is it time to reassess current safety standards for glyphosate-based herbicides?
Abstract: Use of glyphosate-based herbicides (GBHs) increased ∼100-fold from 1974 to 2014. Additional increases are expected due to widespread emergence of glyphosate-resistant weeds, increased application of GBHs, and preharvest uses of GBHs as desiccants. Current safety assessments rely heavily on studies conducted over 30 years ago. We have considered information on GBH use, exposures, mechanisms of …
Genetically modified organisms and biological risks
Text: Widespread distribution of genetically modified organisms (GMO) causes great biological risks for human and the Environment. Three kind of biological risks are described usually: ecological, nutrition and agrotechnical. The term genetically modified organisms (GMOs) refers to plants, microbes and animals with genes transferred from other species in order to produce certain novel characteristics (for …
Uptake of foreign DNA from the environment: The gastrointestinal tract and the placenta as portals of entry
Abstract: Foreign DNA (deoxyribonucleic acid) is part of our environment. Considerable amounts of foreign DNA of very different origin are ingested daily with food. In a series of experiments we fed the DNA of bacteriophage M13 as test DNA to mice and showed that fragments of this DNA survive the passage through the gastrointestinal (GI) …
Perinatal exposure to glyphosate-based herbicide alters the thyrotrophic axis and causes thyroid hormone homeostasis imbalance in male rats
Abstract: Glyphosate-based herbicides (GBHs) are widely used in agriculture. Recently, several animal and epidemiological studies have been conducted to understand the effects of these chemicals as an endocrine disruptor for the gonadal system. The aim of the present study was to determine whether GBHs could also disrupt the hypothalamic-pituitary-thyroid (HPT) axis. Female pregnant Wistar rats …
Herbicide Factsheet 2,4-D
Abstract: 2,4-D is one of the most widely used herbicides in the world. It is commonly used on rangeland and pasture, in the production of wheat, and on home lawns. Symptoms of 2,4-D poisoning in exposed people include irritation and inflammation of eyes and skin, hives, nausea, vomiting, throat irritation, headache, dizziness, coughing, and difficulty …
