Journal or Publishing Institution: Ecotoxicology and Environmental Safety
Study: http://www.sciencedirect.com/science/article/pii/S0147651314002346
Author(s): Samanta, P., Pal, S., Mukherjee, A.K. and Ghosh, A.R.
Article Type: Peer Reviewed Study
Record ID: 2160
Abstract: Effects of glyphosate based herbicide, Excel Mera 71 at a dose of 17.20 mg/l on enzyme activities of acetylcholinesterase (AChE), lipid peroxidation (LPO), catalase (CAT), glutathione-S-transferase (GST) and protein content were measured in different tissues of two Indian air-breathing teleosts, Anabas testudineus (Bloch) and Heteropneustes fossilis (Bloch) during an exposure period of 30 days under laboratory condition. AChE activity was significantly increased in all the investigated tissues of both fish species and maximum elevation was observed in brain of H. fossilis, while spinal cord of A. testudineus showed minimum increment. Fishes showed significant increase LPO levels in all the tissues; highest was observed in gill of A. testudineus but lowest LPO level was observed in muscle of H. fossilis. CAT was also enhanced in both the fishes, while GST activity in liver diminished substantially and minimum was observed in liver of A. testudineus. Total protein content showed decreased value in all the tissues, maximum reduction was observed in liver and minimum in brain of A. testudineus and H. fossilisrespectively. The results indicated that Excel Mera 71 caused serious alterations in the enzyme activities resulting into severe deterioration of fish health; so, AChE, LPO, CAT and GST can be used as suitable indicators of herbicidal toxicity.
Keywords: Acetylcholinesterase, Animals, Biomarkers, Catalase, Catfishes, Fish Proteins, Gills, Glutathione, Glutathione Transferase, Glycine, Herbicides, India, Lipid Peroxidation, Liver, Muscles, Perciformes, Seafood, Excel Mera 71, Teolstean fish, AChE, LPO, CAT, GST, Metabolism, Drug Effects, Analogs & Derivatives, Toxicity, Analysis, Anabas testudineus, Heteropneustes fossilis, brain, enzyme activity, exposure duration, fish health, glyphosate, liver, protein content, spinal cord, tissues, aquatic animals, aquatic organisms, enzymes, aquatic species, cerebrum, ligandin, weedicides, weedkillers
Citation: Samanta, P., Pal, S., Mukherjee, A.K. and Ghosh, A.R., 2014. Biochemical effects of glyphosate based herbicide, Excel Mera 71 on enzyme activities of acetylcholinesterase (AChE), lipid peroxidation (LPO), catalase (CAT), glutathione-S-transferase (GST) and protein content on teleostean fishes. Ecotoxicology and Environmental Safety, 107, pp.120-125.