Journal or Publishing Institution: Reproductive Toxicology
Date of Publication: 03/01/2005
Study: http://www.sciencedirect.com/science/article/pii/S0890623804002059
Author(s): Beuret, C.J., Zirulnik, F., and Giménez, M.S.
Article Type: Peer Reviewed Study
Abstract:
Glyphosate is a post-emergence herbicide that acts on the synthesis of amino acids and other endogenous metabolites in plants. It is commonly used in agriculture, forestry, and nurseries for the control or destruction of herbaceous plants. Metabolic processes during development and pregnancy could be sensitive to changes induced by glyphosate such as lipid peroxidation. The present study has investigated the effects that 1% glyphosate oral exposure has on lipoperoxidation and antioxidant enzyme systems in the maternal serum and liver of pregnant rats and their term fetuses at 21 days of gestation. The results suggest that excessive lipid peroxidation induced with glyphosate ingestion leads to an overload of maternal and fetal antioxidant defense systems.
Keywords: glyphosate, herbicides, pesticides, lipoperoxidation, liver, pregnancy, fetus, rats, rodents, pesticide exposure, toxicity, hepatotoxicity, antioxidants
Citation:
Beuret, C.J., Zirulnik, F., and Giménez, M.S., 2005. Effect of the herbicide glyphosate on liver lipoperoxidation in pregnant rats and their fetuses. Reproductive Toxicology, 19(4), pp. 501–504.
Category:
- Health effects
- Pesticide use
Record ID: 187
