Journal or Publishing Institution: Global NEST Journal
Author(s): Yalçin, E., Acar, A., Seven, B., Taşli, B. and Çavuşoğlu, K.
Article Type: Peer Reviewed Study
Record ID: 1568
Abstract: In this study, we investigated the effects of Genetically Modified (GM) Maize on liver and kidney organ weights, malondialdehyde (MDA) and glutathione (GSH) levels of liver and kidney tissues in New Zealand Rabbits. For this purpose, rabbits were divided into three groups: parental, first-generation and second-generation. Each group was divided into two subgroups i.e. control group and the treatment group. Rabbits on the control group were fed with conventional maize (non-GM), whereas rabbits which are in the treatment groups were fed with GM maize. Six females and six male New Zealand rabbits were used per group. At the end of the experimental period, tissue samples were taken and organ weights, MDA and GSH levels were determined. Overall, as the generations progressed, a statistically significant increase in liver weights and a decrease in kidney weights were observed. There was no statistically significant change as regards MDA and GSH levels of liver and kidney tissues of groups without GM maize inclusion in the diet. However, in all three-generation of GM maize treated groups, there was a significant decrease in GSH levels and a significant increase in MDA levels were observed.
Keywords: genetically modified organism, malondialdehyde, glutathione, feeding, rabbit
Citation: Yalçin, E., Acar, A., Seven, B., Taşli, B. and Çavuşoğlu, K., 2018. Effects of feeding genetically modified (GM) maize on oxidative stress parameters in New Zealand rabbit. Global NEST Journal, 20(1), pp.173-176.
