Journal or Publishing Institution: Journal of Developmental Toxicology
Date of Publication: 06/04/2010
Study: https://web.archive.org/web/20170824185303/https://drithurralde.wordpress.com/2010/06/04/15/
Author(s): Bortagary, V., Aramburu, R., Barrios, L., Ojeda, P., Puerto, G., and Rodríguez-Ithurralde, D.
Article Type: Peer Reviewed Study
Abstract:
A growing body of evidence suggests that herbicides formulated in base of N-(phosphonomethyl)glycine (glyphosate), the most frequently used herbicide in the world, present considerable toxicity for algae, molluscs, fishes and amphybia (Quassinti et al., 2008). Its non-controlled use represents, thererefore, a real menace for biodiversity, natural fishery resources, and pisciculture.
It is of great interest to point out that non-allowed concentrations of this and other herbicides and/or their metabolites and/or coadjuvants have been found in waters and foods for human and/or animal use. In addition, glyphosate final concentrations (ccf) of 3-37 mg/l were found in water samples upon soil infiltration assays and ccf of 0.21-1.51 mg/l were encountered in water samples taken in the vicinity of soils associated with direct sowing soybean cultivation (Peruzzo et al., 2008, 2009). These findings, taken together, are a cause of concern as they show a potential danger for human and animal health, which must be strictly monitored. In addition, the most abundant glyphosate metabolite, the AMPA, is more toxic and more resistant to degradation than glyphosate.
The aim of this work was to investigate and, when possible, quantify using controlled, globally accepted laboratory bioassays, the effects of known concentrations of glyphosate on zebrafish (Danio rerio) development (Hill et al., 2005; Baunbeck & Lammar, 2006).
Keywords: glyphosate, AMPA, pesticides, herbicides, zebrafish, Danio rerio, developmental toxicity
Citation:
Bortagary, V., Aramburu, R., Barrios, L., Ojeda, P., Puerto, G., and Rodríguez-Ithurralde, D., 2010. Embryotoxicity and teratogenesis in zebrafish embryos exposed in vitro to glyphosate-type herbicides. Journal of Developmental Toxicology.
Category:
- Environmental effects
- Pesticide use
Record ID: 237
