Journal or Publishing Institution: British Journal of Cancer
Study: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2011442/
Author(s): Hardell, L. and Bengtsson, N.O.
Article Type: Peer Reviewed Study
Record ID: 924
Abstract: An association between malignant lymphoma (both Hodgkin’s disease (HD) and non-Hodgkin lymphoma) and exposure to organic solvents, phenoxy acids, or chlorophenols was previously reported. A reanalysis of this investigation regarding the cases with HD and exposure to various chemicals was performed and resulted in comparable findings to the whole group of malignant lymphoma. There was an overrepresentation of cases with primary involvement of the gastrointestinal tract which was associated with exposure to these chemicals. The influence of previous diseases and socioeconomic factors was analysed through a supplementary questionnaire to the cases with HD and their matched controls. No differences were found in cases and controls for such variables except for tonsillectomy which was overrepresented among the cases as well as a history of previous duodenal or ventricular ulceration. These findings were, however, insignificant.
Keywords: non-Hodgkin lymphoma, Hodgkin’s disease, exposure, phenoxy acids, chlorophenols, malignancy, carcinogenic effects
Citation: Hardell, L. and Bengtsson, N.O., 1983. Epidemiological study of socioeconomic factors and clinical findings in Hodgkin’s disease, and reanalysis of previous data regarding chemical exposure. British Journal of Cancer, 48(2), p.217.
