Influences of the herbicide glyphosate-isopropylammonium solution on heart activities of Bufo gargarizans

Journal or Publishing Institution: Acta Entomologica Sinica

Study: https://web.archive.org/web/20180812142014/http://www.currentzoology.org/paperdetail.asp?id=6633

Author(s): Xiao, Y., Zhu, S., Li, X. and Jiang, P.

Article Type: Peer Reviewed Study

Record ID: 1563

Abstract: By applying Biological Signal Recording and Monitoring System, this paper aims to study influences of the herbicide glyphosate-isopropylammonium (GIA) on heart rate and electrocardiogram (ECG) of Bufo gargarizans Cantor. GIA solutions sprayed on the toads’ backs are absorbed through the skin and can effect cardiovascular function. Results show that as GIA concentrations increased, heart rate declined and the peak voltage of P wave, R wave and T wave in the ECG decreased. The time of the P-R interval, QRS duration and Q-T interval increased. Heart rate of the toads was statistically correlated with the indexes of the electrocardiogram waveform. Both the relationships between the heart rate and the peak voltage of the waves in ECG waveform and the relationships between the heart rate and the time of the intervals in ECG waveform can be fitted within a multiple linear regression model. The analysis of the multiple linear regression shows that Q-T interval in ECG contributed the most to the pace of heart rate. Because the Q-T interval in ECG waveform is the period for ventricular contraction, it can be deduced that the GIA solution slows down the heart rate of Bufo gargarizans by prolonging ventricular contraction. It can be concluded that the herbicide GIA affects the electronic and mechanical activity of the toad’s heart.

Keywords: Bufo gargarizans Cantor, Glyphosate-isopropylammonium, Heart rate, Electrocardiogram

Citation: Xiao, Y., Zhu, S., Li, X. and Jiang, P., 2007. Influences of the herbicide glyphosate-isopropylammonium solution on heart activities of Bufo gargarizans. Acta Entomologica Sinica, 53(4), pp.668-673.