Journal or Publishing Institution: Nature Biotechnology
Study: http://www.readcube.com/articles/10.1038/nbt0598-401c
Author(s): Stewart Jr, C.N. and Prakash, C.S.
Article Type: Journal Publication
Record ID: 2214
Text: To the editor – The assertion has been made recently by Daniell et al. that chloroplast (cp) transformation will be a practical solution to the problem of crop transgenes flowing to related weeds. This is an overstatement. They argued that transformed cp DNA, which they apparently assumed to exclusively maternally inherited, will not be prone to gene flow through pollen transfer and hybridization compared with genes that are transformed into plant nuclear DNA. From this basis, their report claims that transgenes engineered into the plant cp genome will be biologically contained. While in many species cp transformation will help contain transgenes, this putative panacea is plagued with problems…
Keywords: Chloroplast, Crop Transgenes, Gene Flow, DNA, Hybridization, Plant DNA, Alfalfa, Weeds, Radish, Ruphanus raphanistrum, Biosafety, Canola, Brassicas
Citation: Stewart Jr, C.N. and Prakash, C.S., 1998. Letter 1: Chloroplast-transgenic plants are not a gene flow panacea. Nature Biotechnology, 16(5), p.401.