Journal or Publishing Institution: Journal of Occupational and Environmental Medicine
Author(s): Fortes, C., Mastroeni, S., Segatto, M.M., Hohmann, C., Miligi, L., Bakos, L. and Bonamigo, R.
Article Type: Peer Reviewed Study
Record ID: 700
Abstract: Objective. The objective of the study was to examine the association between occupational exposure to pesticides and cutaneous melanoma, controlling for all possible confounders. Methods. A pooled analysis of two case–control studies was conducted in two different geographic areas (Italy and Brazil). Detailed pesticides exposure histories were obtained. Results. Ever use of any pesticide was associated with a high risk of cutaneous melanoma (odds ratio 2.58; 95% confidence interval 1.18–5.65) in particular exposure to herbicides (glyphosate) and fungicides (mancozeb, maneb), after controlling for confounding factors. When subjects were exposed to both pesticides and occupational sun exposure, the risk increased even more (odds ratio 4.68; 95% confidence interval 1.29–17.0). Conclusions. The study suggests an augmented risk of cutaneous melanoma among subjects with exposure to pesticides, in particular among those exposed to occupational sun exposure.
Citation: Fortes, C., Mastroeni, S., Segatto, M.M., Hohmann, C., Miligi, L., Bakos, L. and Bonamigo, R., 2016. Occupational exposure to pesticides with occupational sun exposure increases the risk for cutaneous melanoma. Journal of Occupational and Environmental Medicine, 58(4), pp.370-375.
