Ovarian growth impairment after chronic exposure to Roundup Ultramax® in the estuarine crab Neohelice granulata

Journal or Publishing Institution: Environmental Science and Pollution Research

Study: https://link.springer.com/article/10.1007/s11356-017-0581-2

Author(s): Canosa, I.S., Silveyra, G.R., Avigliano, L., Medesani, D.A. and Rodríguez, E.M.

Article Type: Peer Reviewed Study

Record ID: 2399

Abstract: Adult females of the estuarine crab Neohelice granulata were exposed to the glyphosate formulation Roundup Ultramax® during the entire 3-month pre-reproductive period. At the end of the assay, a significant higher increment of glycemia was noted at both glyphosate concentrations assayed (0.01 and 0.2 mg/L, acid equivalent). Although no differences were observed in the gonadosomatic index, a significantly higher proportion of reabsorbed vitellogenic oocyte was observed at the highest glyphosate concentration, together with a significant decrease of vitellogenin content in the ovary. In addition, some in vitro assays were carried out by co-incubating small pieces of ovary with or without the addition of Roundup; at both concentrations tested (same as those used in vivo), a decrease in the ovarian vitellogenin content was observed, whereas the ovarian protein synthesis was significantly inhibited by glyphosate at 0.2 mg/L in the Roundup formulation used.

Keywords: Roundup, Glyphosate, Crabs, Ovary, Reproduction, Vitellogenin 

Citation: Canosa, I.S., Silveyra, G.R., Avigliano, L., Medesani, D.A. and Rodríguez, E.M., 2018. Ovarian growth impairment after chronic exposure to Roundup Ultramax® in the estuarine crab Neohelice granulata. Environmental Science and Pollution Research, 25(2), pp.1568-1575.