Journal or Publishing Institution: Elsevier
Study: http://www.sciencedirect.com/science/article/pii/B9780444593894000021
Author(s): López, S.L., Aiassa, D., Benítez-Leite, S., Lajmanovich, R., Manas, F., Poletta, G., Sánchez, N., Simoniello, M.F. and Carrasco, A.E.
Article Type: Report
Record ID: 2129
Abstract: In South America, the incorporation of genetically modified organisms (GMO) engineered to be resistant to pesticides changed the agricultural model into one dependent on the massive use of agrochemicals. Different pesticides are used in response to the demands of the global consuming market to control weeds, herbivorous arthropods, and crop diseases. Here, we review their effects on humans and animal models, in terms of genotoxicity, teratogenicity, and cell damage. We also stress the importance of biomarkers for medical surveillance of populations at risk and propose the use of biosensors as sensitive resources to detect undesirable effects of new molecules and environmental pollutants. The compatibility of glyphosate, the most intensively used herbicide associated to GMO crops, with an integrated pest management for soybean crops, is also discussed.
Keywords: GMO, GMO-based agriculture, glyphosate, pesticides, genotoxicity, teratogenicity, cell damage, human models, animal models, risk, South America
Citation: López, S.L., Aiassa, D., Benítez-Leite, S., Lajmanovich, R., Manas, F., Poletta, G., Sánchez, N., Simoniello, M.F. and Carrasco, A.E., 2012. Pesticides used in South American GMO-based agriculture: A review of their effects on humans and animal models. In Advances in Molecular Toxicology (Vol. 6, pp. 41-75). Elsevier.
