Journal or Publishing Institution: Journal of General Virology
Date of Publication: 06/01/1999
Study: https://jgv.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-80-6-1339?crawler=true
Author(s): Aaziz, R., and Tepfer, M.
Article Type: Journal Publication
Abstract:
Recombination in RNA viruses is a general phenomenon, and is considered to play a major role as a driving force in virus variability and thus in virus evolution. An ever increasing number of RNA viruses has been shown to undergo RNA recombination, whether under natural or experimental conditions. More than 30 years after its discovery, the mechanisms of viral RNA recombination are only now beginning to be elucidated. Recent reports strongly suggest that RNA recombination is linked to virus replication, and that it occurs by a copy-choice mechanism. The detection of recombination between host transcripts and infecting viral RNA genomes has given rise to new concerns about the release of virus-resistant transgenic crops, since recombination could generate viruses with properties different from the infecting strain. We will describe here current knowledge of recombination in RNA viruses, and then will present results showing recombination in transgenic virus-infected plants, and finally will discuss to what extent this may lead to increased variability in plant RNA viruses.
Keywords: RNA, virus, virus resistance, genetically engineered (GE), genetically modified (GM), GMO, transgenic plants, transgenic crops, recombination
Citation:
Aaziz, R., and Tepfer, M., 1999. Recombination in RNA viruses and in virus-resistant transgenic plants. Journal of General Virology, 80(6), 1339-1346.
Category:
- Health effects
- Environmental effects
Record ID: 1
