Study of reproductive function in persons occupationally exposed to 2,4-dichlorophenoxyacetic acid (2,4-D)

Journal or Publishing Institution: Mutation Research

Study: http://www.ncbi.nlm.nih.gov/pubmed/1986284

Author(s): Lerda, D. and Rizzi, R.

Article Type: Peer Reviewed Study

Record ID: 1398

Abstract: We studied the reproductive function of 32 male farm sprayers who were exposed to 2,4-D. Sperm analysis was made after 4 days of sexual inactivity. Parameters analyzed were volume, sperm count, mobility and morphology. Exposure level was estimated by measuring the concentration of 2,4-D in the urine. Significant levels of asthenospermia, necrospermia and teratospermia were found in exposed workers compared with unexposed controls. Over time, asthenospermia and necrospermia diminished but the abnormal spermatozoa (teratospermia) continued.

Keywords: 2,4-Dichlorophenoxyacetic Acid, Reproductive Function, Sperm; Humans, Male, Occupational Exposure, Reproduction, Sperm Count, Sperm Motility, Spermatazoa; Toxicity, Urine, Drug Effects

Citation: Lerda, D. and Rizzi, R., 1991. Study of reproductive function in persons occupationally exposed to 2, 4-dichlorophenoxyacetic acid (2, 4-D). Mutation Research, 262(1), pp.47-50.