Journal or Publishing Institution: Journal of Clinical and Analytical Medicine
Study: https://web.archive.org/web/20160412011738/http://www.jcam.com.tr/files/KATD-983.pdf
Author(s): Hasan Kiliçgün, Cebrail Gürsul, Mukadder Sunar, Gülden Gökşen
Article Type: Peer Reviewed Study
Record ID: 1226
Abstract: Aim: Genetically modified crops have a potential to solve many of the world’s nutrition problems. On the other hand, the impact of these novel crops on environmental, animal and human health should be tested and their risk assessment is required. In this study, the aim of this study was to investigate the positive or possible negative effects of genetically modified maize on offspring rats which were between the start of dry food feeding and the time interval until they reached puberty.
Material and Method: Thirty Wistar albino rats were used in this study. The rats were fed with transgenic Bacillus thuringiensis maize and conventional maize during 40 days. After the experimental period, the length, height and weight of organs and serum chemistry and hematology values were measured.
Results: The length, height and weight of liver, spleen, lung and kidneys in Bacillus thuringiensis maize group of rats were different from those in control and conventional groups. When mean values of serum chemistry and hematology parameters, which were glucose, urea, total protein, cholesterol, triglyceride, very low-density lipoprotein, low-density lipoprotein, calcium, phosphorus, sodium, potassium, chlorine were examined, some obvious differences were found between the rats fed with transgenic maize and its conventional counterpart and control groups.
Discussion: The results of this study showed that Bacillus thuringiensis maize may not only have an effect on the length, height and weight of organs of the maturing term of rats but also lead to alterations in serum chemistry and hematology values.
Keywords: Bt Maize, Genetically Modified Organisms, GMO, Rat, Bt corn, Rodent, Wistar albino rats, Rodents, Transgenic, Genetically Engineered, Feeding, Bacillus thuringiensis
Citation: Hasan Kiliçgün, Cebrail Gürsul, Mukadder Sunar, Gülden Gökşen, 2013. The Comparative Effects of Genetically Modified Maize and Conventional Maize on Wistar rats. Journal of Clinical and Analytical Medicine, 4(2), pp.136-139.
