The metabolic and histological changes of kidneys in female rats and the first generation after consumption of genetically modified soybeans

Journal or Publishing Institution: Scientific Statements Series

Study: https://web.archive.org/web/20180726180913/https://cyberleninka.ru/article/n/metabolicheskie-i-gistologicheskie-izmeneniya-pochek-krys-samok-i-potomkov-1-go-pokoleniya-pri-upotreblenii-v-pischu

Author(s): Gubin-Vakulik, G.I., Gorbach, T.V., Myasoedov, V.V., Kolousova, N.G., and Gopkalov, V,G.

Article Type: Peer Reviewed Study

Abstract:

The influence of addition of genetically modified (GM) soybeans during 2 and 6 months to the standard diet of Wistar female rats on metabolic processes and histological condition of kidney was studied. It was established that the consumption of GM-soybeans during 2 months didn’t cause changes in metabolism of kidney. The consumption of GM-soybeans during 6 months led to the development of metabolic changes such as decreased albumin and total proteins level and elevated urea and creatinine levels in blood serum, decreased concentration of ATP and glycogen in kidney. Intake of GM-soybeans causes histological changes in kidney: development of glomerulonephritis and tubulointerstitial nephritis. The descendents of rats have signs of intrauterine influence on kidney genesis and pathological changes are developed faster.

Keywords: Genetically modified soybeans, Kidneys, Blood serum, Metabolism indices, GM Soy, Glyphosate tolerant soybean, GTS 40-3-2, Wistar rats, Roundup Ready soya, Feeding, Rodent, AST, ALT, total protein, albumin, urea, creatinine, uric acid, Histological, transgenic, genetically engineered, rat, rodents, GMO

Citation:

Gubin-Vakulik, G.I., Gorbach, T.V., Myasoedov, V.V., Kolousova, N.G., and Gopkalov, V,G., 2013. The Metabolic and Histological Changes of Kidneys in Female Rats and the First Generation After Consumption of Genetically Modified Soybeans. Scientific Statements Series: Medicine. Pharmacy, 22(11), pp. 150-155.

Губина-Вакулик, Г.И., Горбач, Т.В., Мясоедов, В.В., Колоусова, Н.Г. and Гопкалов, В.Г., 2013. Метаболические и гистологические изменения почек крыс-самок и потомков 1-го поколения при употреблении в пищу генномодифицированной сои. Научные ведомости Белгородского государственного университета. Серия: Медицина. Фармация, 22(11 (154)).

Category:

• Health effects

Record ID: 859