Journal or Publishing Institution: Current Opinion in Biotechnology
Study: http://www.sciencedirect.com/science/article/pii/S0958166904000291
Author(s): Somers, D.A. and Makarevitch, I.
Article Type: Journal Publication
Record ID: 2183
Abstract: Transgene integration in plants transformed by either Agrobacterium or direct DNA delivery methods occurs through illegitimate recombination (IR). The precise mechanism(s) for IR-mediated transgene integration and the role of host double-strand break repair enzymes remain unknown. A recent wealth of sequenced transgene loci and investigations aimed at genetically dissecting transgene integration mechanism(s) have provided new insights into the process.
Keywords: DNA, DNA Repair, Bacterial DNA, Gene Targeting, Gene Transfer Techniques, Plant Genome, Genetically Modified Plants, Transgenes, Genetics, Metabolism, Methods
Citation: Somers, D.A. and Makarevitch, I., 2004. Transgene integration in plants: poking or patching holes in promiscuous genomes? Current Opinion in Biotechnology, 15(2), pp.126-131.
