Journal or Publishing Institution: Journal of Anatomy
Study: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1570979/
Author(s): Malatesta, M., Caporaloni, C., Rossi, L., Battistelli, S., Rocchi, M.B., Tonucci, F. and Gazzanelli, G.
Article Type: Peer Reviewed Study
Abstract:
No direct evidence that genetically modified (GM) food may represent a possible danger for health has been reported so far; however, the scientific literature in this field is quite poor.Therefore, we investigated the possible effects of a diet containing GM soybean on mouse exocrine pancreas by means of ultrastructural, morphometrical and immunocytochemical analyses. Our observations demonstrate that, although no structural modification occurs in pancreaticacinar cells of mice fed on GM soybean, quantitative changes of some cellular constituents takeplace in comparison to control animals. In particular, a diet containing significant amount of GM food seems to influence the zymogen synthesis and processing.
Keywords: Cell Nuclear, Liver, Genetically Modified Soybean; Aging, Alanine Transminase, Animals, Aspartate Aminotransferases, Body Weight, Cell Nucleolus, Cell Nucleus, Non-Histone Chromosomal Proteins, Rough Endoplasmic Reticulum, Female, Genetically Modified Food, Golgi Apparatus, Hepatocytes, Immunohistochemsitry, Mice, Nuclear Envelope, Nuclear Pore, Small Nuclear Ribonucleoproteins, Secretory Vesicles, Soybeans, Fibrillarin, Alanine Transaminase; Metabolism, Ultrastructure, Enzymology, Metabolism, Mouse, Rodent, Rodents
Citation:
Malatesta, M., Caporaloni, C., Rossi, L., Battistelli, S., Rocchi, M.B., Tonucci, F. and Gazzanelli, G., 2002. Ultrastructural analysis of pancreatic acinar cells from mice fed on genetically modified soybean. Journal of Anatomy, 201(5), pp.409-415.
Category:
- Health effects
Record ID: 1486
