Search Results for: Kidney toxicity
Cytotoxicity on human cells of Cry1Ab and Cry1Ac Bt insecticidal toxins alone or with a glyphosate‐based herbicide
Abstract: The study of combined effects of pesticides represents a challenge for toxicology. In the case of the new growing generation of genetically modified (GM) plants with stacked traits, glyphosate‐based herbicides (like Roundup) residues are present in the Roundup‐tolerant edible plants (especially corns) and mixed with modified Bt insecticidal toxins that are produced by the GM plants …
Safety testing of GM-rice expressing PHA-E lectin using a new animal test design
Abstract: The 90-day animal study is the core study for the safety assessment of genetically modified foods in the SAFOTEST project. The model compound tested in the 90-day study was a rice variety expressing the kidney bean Phaseolus vulgaris lectin agglutinin E-form (PHA-E lectin). Female Wistar rats were given a nutritionally balanced purified diet with …
Biological impact of feeding rats with a genetically modified-based diet
Abstract: This work was conducted in the context of postmarketing biosafety assessment of genetically modified products. It presents a systematic approach based on a chronic toxicity study on Wistar albino rats, with a range of combined parameters including biochemical, histopathological, and cytogenetic to evaluate the negative impact of a genetically modified (GM) diet on animal …
Serum biochemical assessment of hepatic and renal functions of rats during oral exposure to glyphosate with zinc
Abstract: A subchronic toxicity study was carried out to assess hepatic and renal functions of rats during oral exposure to glyphosate with zinc for the period of 8 weeks. Forty-eight Wistar rats used for the study were randomized into six groups of eight Wistar rats each, and each group had equal number of male and …
Exploring the case of GE foods
Abstract: Objectives. After reading this CPE article, the nutrition professional will be able to: (1) Define Substantial Equivalence and discuss why it is a problematic concept; (2) Discuss the factors limiting independent research on GE foods; (3) Identify at least four potential health risks associated with GE crops; (4) Explain how consumers can avoid GE …
Pathology reports on the first cows fed with Bt176 maize (1997–2002)
Abstract: On an independent modern farm followed by certified veterinarians, dairy cows (mean of 62 per year) were maintained in optimized milk production for 3 years each. From 1997 to 2002, just after the commercial release of the first GMO (genetically modified organism) in Europe, genetically modified (GM) Bt176 maize grown on the farm was …
