GMO Research
Abstract: We recently proposed that deficient cellular interactions in endocrine pancreas were a primary cause for cancer. Normally, insulin secreting beta cells release in parallel GABA, for inhibiting neighboring alpha and delta cells, releasing glucagon and somatostatin respectively. A deficiency of GABA release, will lead to a hybrid anaboliccatabolic metabolism, mediated by insulin and glucagon. …
To the editor: In a previous work published 4 years ago, an arrest of tumor cell proliferation was obtained with dichloroacetate, an inhibitor of pyruvate dehydrogenase kinase, aiming to dephosphorylate and activate pyruvate dehydrogenase (PDH) [1]. This observation indicates that it may be useful to act as well, on other tumor cell enzymes that change …
Abstract: настоящее время генетически модифицированные продукты, в том числе и соевые бобы, получили широкое распространение на российском рынке. Генетически модифицированную (ГМ) сою обнаруживают в молочных, мясных, хлебобулочных продуктах, детском питании и даже косметике. До настоящего времени вопрос о безопасности длительного употребления генетически модифицированных организмов для млекопитающих и их потомства остается спорным. По данным ряда авторов …
Abstract: Mice fed genetically modified (GM) soybean were not affected in nutritional performance, but pancreatic microscopic features were disturbed. The mechanisms for these contradictory findings are unknown. This study analysed the histology of acinar pancreatic cells and the expression of pancreatitis-associated protein (PAP) and trypsinogen mRNA in rats fed GM soy protein. Two bioassays were …
Abstract: A huge increase in the incidence and prevalence of chronic diseases has been reported in the United States (US) over the last 20 years. Similar increases have been seen globally. The herbicide glyphosate was introduced in 1974 and its use is accelerating with the advent of herbicide-tolerant genetically engineered (GE) crops. Evidence is mounting …
Abstract: We carried out ultrastructural morphometrical and immunocytochemical analyses on pancreatic acinar cell nuclei from mice fed on genetically modified (GM) soybean, in order to investigate possible structural and molecular modifications of nucleoplasmic and nucleolar constituents. We found a significant lowering of nucleoplasmic and nucleolar splicing factors as well as a perichromatin granule accumulation in …
Abstract: Objective. This study aimed to evaluate the healthy risk of genetically modified (GM) soybeans using a novel approach for functions and safety of food. Method. Different from traditional evaluation of substantial equivalence, three innovations were performed in this study, involving basic diet, evaluation approaches and principle, as well as the clarification of connotation differences …
Abstract: This study shows that a diet including insect-resistant Bt176 maize, fed to 53 ewes and their progeny for 3 years, did not have adverse effects on their health or performance and that no horizontal gene transfer to ruminal microorganisms or animal tissues was detected. No differences were observed regarding performance, reproductive traits, haematological parameters, …
Abstract: The 90-day animal study is the core study for the safety assessment of genetically modified foods in the SAFOTEST project. The model compound tested in the 90-day study was a rice variety expressing the kidney bean Phaseolus vulgaris lectin agglutinin E-form (PHA-E lectin). Female Wistar rats were given a nutritionally balanced purified diet with …
Abstract: Цель исследования. Изучение изменений двенадцатиперстной кишки, поджелудочной железы и печени потомства крыс, получавших генетически модифицированную (ГМ) сою. Материалы и методы. Объект исследования – третье поколение крыс (n=10) получавших (ГМ) сою. Контрольная группа – 10 крыс, получавших стандартный виварный рацион. Морфологический материал подвергался стандартной проводке и заливке в парафин, препараты окрашивали гематоксилин – эозином. На …
Abstract: In the present study, an animal model was established by feeding with maize low-nutrient diets, and the imported genetically modified (GM) soybeans was evaluated through the novel BDI-GS system approaches established for functions and safety of food. The growing healthy ICR mice were selected as subject, the control mice were fed simply with maize …
Abstract: No direct evidence that genetically modified (GM) food may represent a possible danger for health has been reported so far; however, the scientific literature in this field is quite poor.Therefore, we investigated the possible effects of a diet containing GM soybean on mouse exocrine pancreas by means of ultrastructural, morphometrical and immunocytochemical analyses. Our …
Abstract: Background: Genetically modified (GM) organisms have been an issue of intense public concern. Among the different GM organisms, GM plants have attracted a large amount of media attention. Corn used for food has been GM to resist glyphosate herbicide, insect resistance (Bt-corn), and vitamin-enriched corn with increase in β carotene, Vitamin C, and folate. …
Introduction: Glyphosate is a broad-spectrum herbicide widely used to kill unwanted plants both in agriculture and in nonagricultural landscapes. Estimated use in the U.S. is between 19 and 26 million pounds per year. Most glyphosate-containing products are either made or used with a surfactant, chemicals that help glyphosate to penetrate plant cells. Glyphosate-containing products are …
Abstract: Introduction. The prolonged and uncontrolled use of genetically modified foods represents the adverse potential effects and threats to human health. Discussion. Discovered the toxic and allergenic influence of number of transgenic proteins on the human organism. The inhibitors of alpha amylases are strong allergens which form complexes with the ferments of the salivary glands …
Abstract: Freshwater crayfish Cherax quadricarinatus have a high commercial value and are cultured in farms where they are potentially exposed to pesticides. Therefore, we examined the sublethal effects of a 50-day exposure to glyphosate acid and polyoxyethylenamine (POEA), both alone and in a 3:1 mixture, on the growth and energetic reserves in muscle, hepatopancreas and …
