Search Results for: Zebrafish
Glyphosate and Roundup® alter morphology and behavior in zebrafish
Abstract: Glyphosate has become the most widely used herbicide in the world, due to the wide scale adoption of transgenic glyphosate resistant crops after its introduction in 1996. Glyphosate may be used alone, but it is commonly applied as an active ingredient of the herbicide Roundup®. This pesticide contains several adjuvants, which may promote an unknown …
An approach to clarify the effect mechanism of glyphosate on body malformations during embryonic development of zebrafish (Daino rerio)
Abstract: In this study, it has been investigated that the effects of glyphosate, which is a herbicide within organophosphate and unselective widely used in agriculture on enzyme activity of carbonic anhydrase, production of reactive oxygen species, cell apoptosis and body morphology during the embryonic development of zebrafish. To this end, it has been treated embryo …
Glyphosate induces neurotoxicity in zebrafish
Abstract: Glyphosate based herbicides (GBH) like Roundup® are used extensively in agriculture as well as in urban and rural settings as a broad spectrum herbicide. Its mechanism of action was thought to be specific only to plants and thus considered safe and non-toxic. However, mounting evidence suggests that GBHs may not be as safe as …
Quizalofop-P-ethyl exposure increases estrogen axis activity in male and slightly decreases estrogen axis activity in female zebrafish (Danio rerio)
Abstract: The herbicide Quizalofop-P-ethyl (QpE) exerts toxic effects in fish, but limited information is currently available on its effects on the endocrine system. In the current study, adult zebrafish (Danio rerio) were exposed to different concentrations (0, 2, 20, 200 μg/L) of QpE for 30 days. In males, QpE exposure significantly increased plasma estradiol (E2) …
Effect of glyphosate on the sperm quality of zebrafish Danio rerio
Abstract: Glyphosate is a systemic, non-selective herbicide widely used in agriculture worldwide. It acts as an inhibitor of the enzyme 5-enolpyruvylshikimate-3-phosphate synthase by interrupting the synthesis of essential aromatic amino acids. This pathway is not present in animals, although some studies have shown that the herbicide glyphosate can affect fish reproduction. In this study, the …
Genotoxic evaluation of different delta-endotoxins from Bacillus thuringiensis on zebrafish adults and development in early life stages
Abstract: The use of toxins from Bacillus thuringiensis as biopesticides in the biological control of insects and in transgenic plants has increased their availability in the environment. Ecotoxicological evaluations of four delta-endotoxins cry 1Aa, cry 1Ab, cry 1Ac, and cry 2A from B. thuringiensis were carried out on zebrafish Danio rerio to explore the adverse …
Cytotoxicity of the association of pesticides Roundup Transorb® and Furadan 350 SC® on the zebrafish cell line, ZF-L
Abstract: The present study aimed to ascertain the cytotoxicity of pesticides commonly used in rice cultivation, through in vitro assays employing the ZF-L cell line. The in vitro analyses investigated three cellular targets (cell membrane integrity, mitochondrial activity and lysosomal stability) in cells exposed to concentrations of Roundup Transorb® (67.7 μg L(-1), 135.4 μg L(-1) …
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Search the primary studies database using one of the pre-defined keyword searches below. # 2,4-Dichlorophenoxyacetic acid (2,4-D) 35S A Acetylcholinesterase Aegilops cylindrica Aflatoxin Africa African Catfish (Clarias Gariepinus) African clawed frog (Xenopus laevis) Agrobacterium Agroecology Agrostis Agrostis stolonifera Alfalfa (Medicago sativa) Allergy Alpaida Veniliae Amaranthus palmeri Amaranthus tuberculatus Ambrosia artemisiifolia Ambystoma gracile Ambystoma laterale Ambystoma …
Effects of glyphosate on cholinesterase activity of the mussel Perna perna and the fish Danio rerio and Jenynsia multidentata: in vitro studies
Abstract: Although the herbicide glyphosate [N-(phosphonomethyl)glycine] is not classified as an acethylcholinesterase inhibitor, some studies have reported reduction in the acethylcolinesterase activity after in vivo exposure to both its pure form and its commercial formulations. Considering this controversy, the objective of the present study was to investigate, in vitro, the effects of glyphosate exposure on …
Ecotoxicological assessment of glyphosate‐based herbicides: Effects on different organisms
Abstract: Glyphosate‐based herbicides are the most commonly used worldwide because they are effective and relatively nontoxic to nontarget species. Unlimited and uncontrolled use of such pesticides can have serious consequences for human health and ecological balance. The present study evaluated the acute toxicity and genotoxicity of 2 glyphosate‐based formulations, Roundup Original (Roundup) and Glyphosate AKB …
Evidence for behavioral preference toward environmental concentrations of urban-use herbicides in a model adult fish
Keywords: Fish live in waters of contaminant flux. In three urban, fish-bearing waterways of British Columbia, Canada, we found the active ingredients of WeedEx, KillEx, and Roundup herbicide formulations (2,4-D, dicamba, glyphosate, and mecoprop) at low to high ng/L concentrations (0.26 to 309 ng/L) in routine conditions, i.e., no rain for at least one week. …
Genetic engineering of animals: Ethical issues, including welfare concerns
Text: The genetic engineering of animals has increased significantly in recent years, and the use of this technology brings with it ethical issues, some of which relate to animal welfare — defined by the World Organisation for Animal Health as “the state of the animal…how an animal is coping with the conditions in which it …
Dietary safety assessment of Flk1-transgenic fish
Abstract: Genetic engineering, also called genetic modification, is facing with growing demands of aquaculture and aquatic products. Although various genetically modified (GM) aquatics have been generated, it is important to evaluate biosafety of GM organisms on the human health before entering into our food chain. For this purpose, we establish a zebrafish wild adult feeding …
Why genetically modified food needs reconsideration before consumption
Text: Introduction. With the advent of introducing genetic engineering in agricultural sciences and food production, food safety has become a major issue.[1] The genetic content of the organisms is altered using these techniques that result into genetically engineered organism (plants/animals) also known as genetically modified organisms. Human beings mainly depend upon plants for their food …